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Time–Frequency Analysis of The Second Heart Sound to Assess Pulmonary Artery Pressure
Acoustical Physics ( IF 0.9 ) Pub Date : 2020-09-17 , DOI: 10.1134/s1063771020050012
V. G. Andreev , V. V. Gramovich , M. V. Krasikova , A. I. Korolkov , O. N. Vyborov , N. M. Danilov , T. V. Martynyuk , O. V. Rodnenkov , O. V. Rudenko

A method is proposed for noninvasive assessment of the pulmonary artery pressure based on separation of the aortic and pulmonary components of the second heart sound S2 and determining the delay time between them. The algorithm for separating the aortic and pulmonary components is based on the Wigner–Ville transform. Analysis of the phonocardiograms of 96 patients with pulmonary hypertension (PH) recorded by doctors of the Scientific Research Center of Cardiology using an original set of equipment was carried out. In 53 patients with PH, it was possible to separate S2 signals into components and determine the delays between them. We construct the dependence of delays between the components on pulmonary artery pressure (PAP), measured by right heart catheterization (RHC). For seven patients with PH, the obtained dependences were used to predict the PAP value from the measured time delay. For five patients, the determination coefficient for the predicted PAP values was 0.83, which indicates a fairly good correlation with measurements by the RHC method.



中文翻译:

第二心音评估肺动脉压的时频分析

提出了一种基于第二心音S 2的主动脉和肺部成分的分离并确定它们之间的延迟时间来无创评估肺动脉压力的方法。分离主动脉和肺部分的算法基于Wigner-Ville变换。使用原始设备对由心脏病学科学研究中心的医生记录的96例肺动脉高压(PH)患者的心电图进行了分析。在53例PH患者中,有可能分离出S 2信号进入组件并确定它们之间的延迟。我们构建了组件之间的延迟对肺动脉压(PAP)的依赖性,通过右心导管检查(RHC)测量。对于7例PH患者,使用获得的依赖性从测量的时间延迟中预测PAP值。对于五名患者,PAP预测值的确定系数为0.83,这表明与RHC方法的测量值具有相当好的相关性。

更新日期:2020-09-17
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