The antimicrobial and antifungal activity of polymers used in medical devices has been extensively studied due to the growing impact of hospital-related infections in patients. The ideal biocidal polymeric materials should be very effective in the microorganism’s inhibition, not toxic to the human body, and environmentally friendly. In this context, this work is aimed at obtaining antimicrobial and antifungal properties at the polyester film surfaces without introducing toxic effects. Poly (ethylene terephthalate) (PET) films were functionalized with Ar plasma and then immersed in a solution containing gold nanoparticles (AuNps). The results demonstrated the appearance of the hydrophilic groups on the film surface after modification of PET film by plasma Ar treatment and the formation of the polar groups such as C=O, COO-, and OH, which then reacted with AuNps. The changes induced in the treated polymer samples were investigated in terms of AuNp adsorption efficiency on polyester film by contact angle, profilometry, Scanning Electron Microscopy (SEM), Attenuated Total Reflectance Spectroscopy-Fourier Transform Infrared (ATR-FTIR), and X-ray Photoelectron Spectroscopy (XPS) measurements. The morphological and structural analyses have shown a good adhesion of AuNps at treated film surfaces. The results of biocompatibility antimicrobial and antifungal tests proved the nontoxic behavior of the sample and its good antimicrobial and antifungal activity.

中文翻译：

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获得具有抗菌特性的镀金聚酯表面的简便方法

由于医院相关感染对患者的影响越来越大，医疗器械中使用的聚合物的抗菌和抗真菌活性已得到广泛研究。理想的生物杀灭高分子材料应该对微生物的抑制非常有效，对人体无毒，对环境友好。在这种情况下，这项工作的目的是在聚酯薄膜表面获得抗菌和抗真菌特性，而不引入毒性作用。聚对苯二甲酸乙二酯 (PET) 薄膜用 Ar 等离子体功能化，然后浸入含有金纳米颗粒 (AuNps) 的溶液中。结果表明，PET薄膜经等离子Ar处理后，薄膜表面出现亲水基团，并形成C=O、COO-、OH等极性基团，然后与 AuNps 反应。通过接触角、轮廓测定法、扫描电子显微镜 (SEM)、衰减全反射光谱 - 傅立叶变换红外 (ATR-FTIR) 和 X 射线，研究了处理后的聚合物样品在聚酯膜上的 AuNp 吸附效率方面的变化光电子能谱 (XPS) 测量。形态和结构分析表明，AuNps 在处理过的薄膜表面具有良好的附着力。生物相容性抗菌和抗真菌试验的结果证明了样品的无毒行为及其良好的抗菌和抗真菌活性。衰减全反射光谱-傅立叶变换红外 (ATR-FTIR) 和 X 射线光电子光谱 (XPS) 测量。形态和结构分析表明，AuNps 在处理过的薄膜表面具有良好的附着力。生物相容性抗菌和抗真菌试验的结果证明了样品的无毒行为及其良好的抗菌和抗真菌活性。衰减全反射光谱-傅立叶变换红外 (ATR-FTIR) 和 X 射线光电子光谱 (XPS) 测量。形态和结构分析表明，AuNps 在处理过的薄膜表面具有良好的附着力。生物相容性抗菌和抗真菌试验的结果证明了样品的无毒行为及其良好的抗菌和抗真菌活性。