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Identifying Plant-Based Natural Medicine against Oxidative Stress and Neurodegenerative Disorders
Oxidative Medicine and Cellular Longevity Pub Date : 2020-09-16 , DOI: 10.1155/2020/8648742
Rahul Chandran 1 , Heidi Abrahamse 1
Affiliation  

Free radicals and oxidative stress are among the most studied factors leading to the imbalance in mental health. With no exception, free radicals also damage neuronal cells, leading to various degenerative diseases. With existing modern medications, around 80% of the world population relies on herbal medicine for various ailments. Phytochemicals in plants have a wide range of pharmacological properties, the major being their ability to scavenge free radicals. Plant polyphenols are among the major class of antioxidants identified in plants. This antioxidative property of plant compounds and their ability to downgrade the process of oxidative stress can be used to treat neurodegenerative diseases. However, selecting plants and their active compounds is a crucial step in framing the mechanism of action underlying their therapeutic potential.

中文翻译:

确定针对氧化应激和神经退行性疾病的植物性天然药物

自由基和氧化应激是导致心理健康失衡的最受研究的因素。自由基无一例外也破坏神经元细胞,导致各种退行性疾病。使用现有的现代药物,全世界约80%的人口依赖各种疾病的草药。植物中的植物化学物质具有广泛的药理特性,主要是其清除自由基的能力。植物多酚是植物中鉴定出的主要抗氧化剂之一。植物化合物的这种抗氧化特性及其降低氧化应激过程的能力可用于治疗神经退行性疾病。然而,选择植物及其活性化合物是确定其潜在治疗作用机理的关键步骤。
更新日期:2020-09-16
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