Introduction: In recent years, resource-saving handling of allogeneic blood products and a reduction of transfusion rates in adults has been observed. However, comparable published national data for transfusion practices in pediatric patients are currently not available. In this study, the transfusion rates for children and adolescents were analyzed based on data from the Federal Statistical Office of Germany during the past 2 decades. Methods: Data were queried via the database of the Federal Statistical Office (Destasis). The period covered was from 2005 to 2018, and those in the sample group were children and adolescents aged 0–17 years receiving inpatient care. Operation and procedure codes (OPS) for transfusions, procedures, or interventions with increased transfusion risk were queried and evaluated in detail. Results: In Germany, 0.9% of the children and adolescents treated in hospital received a transfusion in 2018. A reduction in transfusion rates from 1.02% (2005) to 0.9% (2018) was observed for the total collective of children and adolescents receiving inpatient care. Increases in transfusion rates were recorded for 1- to 4- (1.41–1.45%) and 5- to 10-year-olds (1.24–1.33%). Children under 1 year of age were most frequently transfused (in 2018, 40.2% of the children were cared for in hospital). Transfusion-associated procedures such as chemotherapy or machine ventilation and respiratory support for newborns and infants are on the rise. Conclusion: Transfusion rates are declining in children and adolescents, but the reasons for increases in transfusion rates in other groups are unclear. Prospective studies to evaluate transfusion rates and triggers in children are urgently needed.

中文翻译：

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随着时间的推移，儿童和青少年输血实践的变化

简介：近年来，已经观察到同种异体血液制品的资源节约处理和成人输血率的降低。然而，目前尚无关于儿科患者输血实践的可比国家数据。在这项研究中，根据德国联邦统计局过去 20 年的数据分析了儿童和青少年的输血率。方法：通过联邦统计局（Destasis）的数据库查询数据。覆盖时期为 2005 年至 2018 年，样本组为接受住院治疗的 0-17 岁儿童和青少年。对输血、程序或输血风险增加的干预措施的操作和程序代码（OPS）进行了详细查询和评估。结果：在德国，0。2018 年，住院治疗的儿童和青少年中有 9% 接受了输血。接受住院治疗的儿童和青少年的总输血率从 1.02%（2005 年）降低到 0.9%（2018 年）。1 至 4 岁（1.41-1.45%）和 5 至 10 岁儿童（1.24-1.33%）的输血率增加。1 岁以下儿童输血频率最高（2018 年，40.2% 的儿童在医院接受治疗）。新生儿和婴儿的化疗或机器通气和呼吸支持等输血相关程序正在增加。结论：儿童和青少年的输血率正在下降，但其他组输血率上升的原因尚不清楚。