We present a mode localized mass sensor prototype based on a hybrid system excited at a fixed frequency slightly below the resonances. Indeed, we show, both theoretically and experimentally, that this condition yields higher sensitivities and similar sensitivity ranges than that of resonance peak tracking while being less time consuming than a classical open-loop configuration due to the absence of frequency sweep. The system is made of a quartz resonator and a hardware that includes a resonator and the coupling. The digital aspect allows maximum sensitivity to be achieved with a fine tuning of the different parameters and the implementation of a coupling, regardless of the physical resonator geometry. This allows the generation of mode localization on shear waves resonant structures such as the quartz cristal microbalance widely used in biosensing. This solution has been successfully implemented using resin micro balls depositions. The sensitivities reach almost their maximum theoretical values which means this fixed frequency method has the potential to reach lower limit of detection than the open loop frequency tracking method.

中文翻译：

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迈向基于模式定位且无需共振跟踪的超灵敏混合质量传感器。

我们提出了一种基于混合系统的模式局部质量传感器原型，该混合系统在固定频率下稍低于共振的条件下激发。实际上，无论是从理论上还是从实验上，我们都表明，这种条件比共振峰跟踪具有更高的灵敏度和相似的灵敏度范围，同时由于没有扫频，因此比传统的开环配置更省时。该系统由石英谐振器和包括谐振器和耦合器的硬件组成。无论物理谐振器的几何形状如何，数字方面都可以通过对不同参数的精细调整和耦合的实现来实现最大的灵敏度。这允许在剪切波谐振结构（如广泛用于生物传感的石英晶体微天平）上产生模式定位。使用树脂微球沉积已成功实现了该解决方案。灵敏度几乎达到其最大理论值，这意味着该固定频率方法比开环频率跟踪方法具有达到检测下限的潜力。