Nanoscale Supramolecular Probes for the Naked-Eye Detection of Illicit Drugs,ACS Applied Nano Materials

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Nanoscale Supramolecular Probes for the Naked-Eye Detection of Illicit Drugs
ACS Applied Nano Materials ( IF 5.3 ) Pub Date : 2020-09-16 , DOI: 10.1021/acsanm.0c02370
Daniele Rosa-Gastaldo ₁ , Angelo Scopano ₁ , Marco Zaramella ₁ , Fabrizio Mancin ₁

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The identification of psychoactive substances, in particular of designer drugs, on the site of their discovery is crucial to contrast the diffusion of drugs of abuse. We report here the first example of a nanoscale colorimetric probe, based on the nanoconfinement of a tricyclic dye and the target analytes in the cavity of cucurbit[8]uril. The probe selectively responds to N-(2-methoxybenzyl)phenethylamines, with a limit of detection of 3 μM. The sensing system can be deposited on paper, thus obtaining a colorimetric strip test capable of discriminating illegal drugs from other substances of common use.

中文翻译：

纳米级超分子探针用于裸眼检测非法药物

在发现精神活性物质，特别是名牌药物的过程中，对识别精神活性物质至关重要，以与滥用药物的扩散形成对比。我们在此报告纳米级比色探针的第一个示例，该示例基于三环染料和葫芦丝[8] uril腔中目标分析物的纳米约束。探针选择性地响应N-（2-甲氧基苄基）苯乙胺，检测限为3μM。感测系统可以沉积在纸上，从而获得比色条测试，能够将非法药物与其他常用物质区分开。

更新日期：2020-10-25

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