ABSTRACT The objective of this study was to investigate effects of silicate (SIL) supplementation on growth performance, nutrient digestibility, organ weight, immune traits, fecal microbiota, rectal temperature, and diarrhea score in weaning to growing pigs with challenged lipopolysaccharide (LPS). In experiment 1, a total of 72 piglets [(Landrace × Yorkshire) × Duroc] with initial body weight (BW) of 7.53 ± 0.1 kg were used in 14 weeks. Treatment groups: (1) Basal diet (CON), and (2) Basal diet + 0.1% silicate (SIL). In experiment 2, after reaching an average BW of 28.12 ± 0.79 kg at end of this experiment, 24 piglets in each treatment (12 pigs per treatment and 2 pigs per pen) were challenged with 100 μg/kg LPS. In experiment 1, SIL diets improved (P < 0.05) growth performance, crude protein (CP) digestibility and reduced (P < 0.05) NH3 emission compared to CON diet. In experiment 2, after piglets were fed SIL diets, numbers of white blood cells (WBCs) such as WBC, neutrophil, monocyte, and lymphocyte were increased (P < 0.05). SIL diets decreased (P < 0.05) cortisol level, Escherichia coli count, diarrhea incidence, and rectal temperature compared to CON diet.

中文翻译：

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补充石英斑岩硅酸盐对脂多糖攻击后断奶仔猪健康的影响

摘要 本研究的目的是研究添加硅酸盐 (SIL) 对生长性能、营养物质消化率、器官重量、免疫特性、粪便微生物群、直肠温度和断奶时的腹泻评分的影响。在实验1中，14周内共使用了72头仔猪[（长白×约克夏）×杜洛克]，初始体重（BW）为7.53±0.1 kg。治疗组：(1) 基础饮食 (CON)，和 (2) 基础饮食 + 0.1% 硅酸盐 (SIL)。在实验 2 中，在该实验结束时达到 28.12 ± 0.79 kg 的平均体重后，每个处理中的 24 头仔猪（每个处理 12 头猪和每个围栏 2 头猪）用 100 μg/kg LPS 进行攻击。在实验 1 中，SIL 日粮提高了 (P < 0.05) 生长性能、粗蛋白 (CP) 消化率并降低了 (P < 0. 05) 与 CON 饮食相比的 NH3 排放。在实验2中，仔猪饲喂SIL日粮后，白细胞（WBC）的数量增加，如白细胞、中性粒细胞、单核细胞和淋巴细胞（P < 0.05）。与 CON 饮食相比，SIL 饮食降低了（P < 0.05）皮质醇水平、大肠杆菌计数、腹泻发生率和直肠温度。