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Polydopamine Nanoparticles: Efficient Cellular Internalization and Transport of Bowl‐Shaped Polydopamine Particles (Part. Part. Syst. Charact. 9/2020)
Particle & Particle Systems Characterization ( IF 2.7 ) Pub Date : 2020-09-16 , DOI: 10.1002/ppsc.202070020
Shahinur Acter 1 , Mark Louis P. Vidallon 1 , Simon Crawford 2 , Rico F. Tabor 1 , Boon Mian Teo 1
Affiliation  

In article number 2000166, Boon Mian Teo and co‐workers synthesize polydopamine bowl‐shaped nanoparticles via an emulsion‐induced interfacial assembly method. Incubation of bowl‐shaped particles with HeLa cells demonstrate that they adhere to the cells more efficiently and exhibit higher rate of cellular uptake compared to their spherical counterparts. This highlights that cellular uptake of particles is shape dependent and have crucial implications in the design of efficient drug carriers.
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中文翻译:

聚多巴胺纳米颗粒:碗状聚多巴胺颗粒的高效细胞内在化和运输(部分,系统特性9/2020)

在编号2000166的文章中,Boon Mian Teo及其同事通过乳液诱导界面组装方法合成了聚多巴胺碗状纳米颗粒。碗状颗粒与HeLa细胞的孵育表明,与球形的相比,它们更有效地粘附于细胞,并具有更高的细胞摄取率。这突显了细胞对颗粒的摄取取决于形状,并且对有效药物载体的设计具有至关重要的意义。
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更新日期:2020-09-16
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