Some epidemiological studies have suggested that exposure to extremely low‐frequency magnetic fields (ELF‐MFs) can affect the immune system. This study aimed to investigate the effects of antioxidant vitamin consumption on proinflammatory cytokines and biochemical parameters changes. In this randomized, controlled double‐blinded trial study, power plant workers exposed to ELF‐MFs were enrolled based on inclusion criteria. Ninety‐one eligible subjects were randomly divided into four groups: the first group (400 units of vitamin E/day), second group (1,000 mg of vitamin C/day), third group (400 units of vitamin E and 1,000 mg of vitamin C/day), and control group. The intervention was conducted for 3 months. Proinflammatory cytokines interleukin‐1β (IL‐1β), IL‐6, and tumor necrosis factor‐α (TNF‐α), and biochemical parameters (fasting blood sugar, total cholesterol, triglyceride, low‐density lipoprotein cholesterol, high‐density lipoprotein cholesterol [HDL‐c], total protein, and albumin) were measured among the participants’ serums, before and after the intervention. The mean level of IL‐6 in all vitamin‐receiving groups, the mean level of IL‐1β in vitamin C and E&C groups, and the mean level of TNF‐α in the vitamin C group, decreased significantly after intervention. The arithmetic means of the effect sizes for IL‐1β, IL‐6, and TNF‐α were 0.71, 0.57, and 0.2, respectively. The level of HDL‐c in the vitamin E and vitamin E&C groups and the level of triglyceride in the vitamin C group significantly increased after the intervention. Taking antioxidant vitamins can prevent an increase of proinflammatory cytokines induced by prolonged exposure to ELF‐MFs. Bioelectromagnetics. 2021;42:18–26. © 2020 Bioelectromagnetics Society

中文翻译：

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抗氧化维生素对发电厂工人促炎细胞因子和一些生化参数的影响：一项双盲随机对照临床试验。

一些流行病学研究表明，暴露于极低频磁场 (ELF-MF) 会影响免疫系统。本研究旨在研究抗氧化维生素消耗对促炎细胞因子和生化参数变化的影响。在这项随机、对照双盲试验研究中，根据纳入标准招募了暴露于 ELF-MF 的发电厂工人。91 名符合条件的受试者被随机分为四组：第一组（400 单位维生素 E/天）、第二组（1,000 毫克维生素 C/天）、第三组（400 单位维生素 E 和 1,000 毫克维生素 C/天）。 C/天）和对照组。干预进行了3个月。促炎细胞因子白细胞介素-1β (IL-1β)、IL-6 和肿瘤坏死因子-α (TNF-α) 和生化参数（空腹血糖、在干预前后测量参与者血清中的总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇 [HDL-c]、总蛋白和白蛋白）。干预后，所有维生素接受组的 IL-6 平均水平、维生素 C 和 E&C 组的 IL-1β 平均水平以及维生素 C 组的平均 TNF-α 水平均显着降低。IL-1β、IL-6 和 TNF-α 效应量的算术平均值分别为 0.71、0.57 和 0.2。干预后维生素E组和维生素E&C组的HDL-c水平和维生素C组的甘油三酯水平显着升高。服用抗氧化维生素可以防止长时间暴露于 ELF-MF 诱导的促炎细胞因子的增加。生物电磁学。2021;42：18-26。© 2020 生物电磁学学会