Introduction Delirium and catatonia are two representations of acute brain dysfunction that can occur in medically ill patients. It has become increasingly evident that delirium and catatonia can co-occur in the setting of medical illnesses. Delirium and catatonia have been separately described as neuropsychiatric sequelae of Coronavirus Disease 2019 (COVID-19) infection; however, to the best of our knowledge the co-occurrence of delirium and catatonia in the setting of COVID-19 has not been previously reported. Case We describe a case of concurrent delirium and catatonia in a 70-year-old woman with multiple medical comorbidities but with no prior psychiatric history, who was hospitalized with COVID-19 pneumonia. Her symptoms of both delirium and catatonia improved with administration of low-dose lorazepam. Discussion We highlight the importance of recognizing catatonia in medically ill patients and the overlap between and co-occurrence of delirium and catatonia in this population. We explore how the conditions imposed by COVID-19 illness and its unique pathophysiology predispose patients to the development of both delirium and catatonia, as well as the challenges imposed by traditionally different approaches to treatment of these two conditions. Conclusion Delirium and catatonia can co-occur in the context of acute COVID-19 illness. Features specific to COVID-19, both pathophysiological and environmental, create a unique set of conditions, which predispose patients to co-occurring delirium and catatonia. Delirium and co-occurring catatonia may improve with administration of low-dose lorazepam in selected patients.

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一名 COVID-19 妇女并发谵妄和紧张症一例

简介 谵妄和紧张症是急性脑功能障碍的两种表现，可能发生在疾病患者身上。越来越明显的是，谵妄和紧张症可以在医疗疾病的情况下同时发生。谵妄和紧张症已分别描述为 2019 年冠状病毒病 (COVID-19) 感染的神经精神后遗症；然而，据我们所知，在 COVID-19 的情况下，谵妄和紧张症的共同发生以前没有报道过。病例我们描述了一名患有多种医学合并症但既往无精神病史的 70 岁女性并发谵妄和紧张症的病例，该女性因 COVID-19 肺炎住院。服用低剂量劳拉西泮后，她的谵妄和紧张症症状得到改善。讨论 我们强调了识别内科患者紧张症的重要性，以及该人群中谵妄和紧张症之间的重叠和同时发生。我们探讨了 COVID-19 疾病及其独特的病理生理学造成的疾病如何使患者易患谵妄和紧张症，以及传统上不同的治疗这两种疾病的方法所带来的挑战。结论 谵妄和紧张症可在急性 COVID-19 疾病的背景下同时发生。COVID-19 特有的病理生理和环境特征创造了一组独特的条件，使患者容易同时发生谵妄和紧张症。在选定的患者中使用低剂量劳拉西泮可能会改善谵妄和同时发生的紧张症。我们探讨了 COVID-19 疾病及其独特的病理生理学造成的疾病如何使患者易患谵妄和紧张症，以及传统上不同的治疗这两种疾病的方法所带来的挑战。结论 谵妄和紧张症可在急性 COVID-19 疾病的背景下同时发生。COVID-19 特有的病理生理和环境特征创造了一组独特的条件，使患者容易同时发生谵妄和紧张症。在选定的患者中使用低剂量劳拉西泮可能会改善谵妄和同时发生的紧张症。我们探讨了 COVID-19 疾病及其独特的病理生理学造成的疾病如何使患者易患谵妄和紧张症，以及传统上不同的治疗这两种疾病的方法所带来的挑战。结论 谵妄和紧张症可在急性 COVID-19 疾病的背景下同时发生。COVID-19 特有的病理生理和环境特征创造了一组独特的条件，使患者容易同时发生谵妄和紧张症。在选定的患者中使用低剂量劳拉西泮可能会改善谵妄和同时发生的紧张症。结论 谵妄和紧张症可在急性 COVID-19 疾病的背景下同时发生。COVID-19 特有的病理生理和环境特征创造了一组独特的条件，使患者容易同时发生谵妄和紧张症。在选定的患者中使用低剂量劳拉西泮可能会改善谵妄和同时发生的紧张症。结论 谵妄和紧张症可在急性 COVID-19 疾病的背景下同时发生。COVID-19 特有的病理生理和环境特征创造了一组独特的条件，使患者容易同时发生谵妄和紧张症。在选定的患者中使用低剂量劳拉西泮可能会改善谵妄和同时发生的紧张症。