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Generation and characterization of two induced pluripotent stem cell lines (NUIGi038-A, NUIGi038-B) from dermal fibroblasts of a healthy individual
Stem Cell Research ( IF 0.8 ) Pub Date : 2020-09-16 , DOI: 10.1016/j.scr.2020.101996 Ning Ge 1 , Min Liu 2 , Xiaoran Zhu 3 , Janusz Krawczyk 4 , Veronica McInerney 5 , Sanbing Shen 1 , Timothy O'Brien 1 , Terence Prendiville 6
中文翻译：
从健康个体的皮肤成纤维细胞中生成两种诱导性多能干细胞系（NUIGi038-A，NUIGi038-B）并进行表征
更新日期：2020-09-28
Stem Cell Research ( IF 0.8 ) Pub Date : 2020-09-16 , DOI: 10.1016/j.scr.2020.101996 Ning Ge 1 , Min Liu 2 , Xiaoran Zhu 3 , Janusz Krawczyk 4 , Veronica McInerney 5 , Sanbing Shen 1 , Timothy O'Brien 1 , Terence Prendiville 6
Affiliation
Abstract
Two human induced pluripotent stem cell (hiPSC) lines (NUIGi038-A, NUIGi038-B) were generated from dermal fibroblasts of a healthy 47 year old female using non-integrational Sendai reprogramming method expressing OCT4, SOX2, KLF4 and C-MYC. Characterization of both hiPSC lines was confirmed by the expression of typical pluripotency markers and differentiation potential in vitro.
中文翻译：
从健康个体的皮肤成纤维细胞中生成两种诱导性多能干细胞系（NUIGi038-A，NUIGi038-B）并进行表征
摘要
使用表达OCT4，SOX2，KLF4和C-MYC的非整合仙台重编程方法，从健康的47岁女性的皮肤成纤维细胞中生成了两条人类诱导的多能干细胞（hiPSC）系（NUIGi038-A，NUIGi038-B）。两种hiPSC系的特性均由典型的多能性标记物的表达和体外分化潜能证实。
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