It is a great challenge to assemble low-cost and recyclable surface enhanced Raman scattering (SERS) substrates for sensitive detection towards target analytes. In this work, a 3D core-shell Cu₂O@SiO₂@zinc 2-methylimidazolate metal-organic frameworks@Ag nanocomposite (Cu₂O@SiO₂@ZIF-8@Ag) was facilely fabricated only with 0.5 wt.% Ag. The successful construction of the novel Cu₂O-based SERS platform with special structure was confirmed by scanning electron microscopy, transmission electron microscopy, X-ray powder diffraction, and X-ray photoelectron spectroscopy. It showed that the nanocomposite can offer high-dispersion and small size Ag NPs implanted on the Cu₂O@SiO₂@ZIF-8, thus providing high-density hotspots. Importantly, the nanocomposite exhibited a highly sensitive and stable SERS response toward crystal violet (CV, a dose-related carcinogen) molecules. Especially, it can be detected as low as 1 × 10⁻¹⁹ M. The considerable SERS enhancement over the nanocomposite was owed to the special Ag and the powerful enrichment effect of the ZIF-8 shell sustained by the Cu₂O@SiO₂ core. Moreover, with the nanocomposite as the SERS substrate towards CV detection, the high SERS performance was still kept even after 15 cycles and even after placed in the air for 40 days. Additionally, a little silver and good selectivity were both significant for reliable quantitative detection in practical application.

组装低成本，可回收的表面增强拉曼散射（SERS）底物以对目标分析物进行灵敏检测是一个巨大的挑战。在这项工作中，仅用0.5 wt。％的含量即可轻松制备3D核-壳Cu ₂ O @ SiO ₂ @ _2-甲基咪唑锌金属-有机骨架@ Ag纳米复合材料（Cu ₂ O @ SiO ₂ @ ZIF-8 @ Ag）。银 通过扫描电子显微镜，透射电子显微镜，X射线粉末衍射和X射线光电子能谱证实了具有特殊结构的新型Cu ₂ O基SERS平台的成功构建。结果表明，该纳米复合材料可以提供高分散性和小尺寸的Ag NPs注入到Cu ₂ O @ SiO _2上@ ZIF-8，因此提供了高密度的热点。重要的是，纳米复合材料对结晶紫（CV，剂量相关的致癌物）分子表现出高度敏感和稳定的SERS反应。特别是，它可以为1×10被检测为低^-19 M的相当大的SERS增强在所述纳米复合材料被欠特殊的Ag和ZIF-8壳的强大效果富集持续通过将Cu ₂ ö@的SiO ₂芯。此外，使用纳米复合材料作为用于CV检测的SERS底物，即使经过15个循环，甚至在空气中放置40天后，仍能保持较高的SERS性能。另外，少量的银和良好的选择性对于实际应用中的可靠定量检测都是重要的。