The ulexite (UX), a borate mineral, is used as boron source and commonly used in various industrial processes. The hematological and hepatic effects of UX were investigated by exposing adult zebrafish to UX (5, 10, 20 and 40 mg/L) over 96 hours. The blood and liver tissues were taken at the end of the trial period then micronucleus (MN) rates, oxidative DNA damage (8-OHdG), apoptosis (Caspase-3), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), myeloperoxidase (MPO), paraoxonase (PON), arylesterase (AR) and lipid peroxidation (MDA) levels were determined. Genotoxic damage by UX occurred only at 40 mg/L in the blood MN assay. Oxidative stress, oxidative DNA damage and apoptosis in liver also occurred at this dose. Moreover, 5-20 mg/L doses led to decreases of DNA damage and apoptosis levels via promoting antioxidant system in liver tissues. UX exhibits beneficial roles on blood and liver tissues of zebrafish at relatively lower doses, which may be relevant to nutritional and medicinal industries.

硼砂矿方钠石（UX）用作硼源，通常用于各种工业过程中。通过将成年斑马鱼在96小时内暴露于UX（5、10、20和40 mg / L）来研究UX的血液学和肝功能。在试验期结束时采集血液和肝组织，然后采集微核（MN）速率，氧化性DNA损伤（8-OHdG），凋亡（Caspase-3），超氧化物歧化酶（SOD），过氧化氢酶（CAT），谷胱甘肽过氧化物酶测定（GPx），髓过氧化物酶（MPO），对氧磷酶（PON），芳基酯酶（AR）和脂质过氧化（MDA）的水平。在血液MN分析中，UX的基因毒性损害仅在40 mg / L时发生。在该剂量下也发生肝中的氧化应激，氧化性DNA损伤和细胞凋亡。此外，5-20 mg / L剂量通过促进肝组织中的抗氧化剂系统导致DNA损伤和凋亡水平降低。UX在相​​对较低的剂量下对斑马鱼的血液和肝脏组织表现出有益的作用，这可能与营养和医药行业有关。