Gel formation using guanosine self-assembly is an important process in supramolecular chemistry. Here, we report the stepwise construction of circularly polarized luminescent supramolecular organogels from self-assembled guanosine quadruplexes. A lipophilic guanosine derivative (aldG) is designed and synthesized for the formation of a well-defined G₈-octamer. The diamine linkers are used to connect G₈-octamer units by imine formation to facilitate the construction of the supramolecular gel networks. ¹H NMR experiments show that the pre-assembled aldG₈-octamer remains intact and is crucial for transparent and stiff organogel formation. With extended conjugation, the aldG organogels exhibit strong green fluorescence emission and circularly polarized properties without the assistance of any external fluorescent dyes, suggesting an alternative approach to construct molecular probes for biological and material applications.

利用鸟苷自组装形成凝胶是超分子化学中的一个重要过程。在这里，我们报告了从自组装鸟苷四链体逐步构建圆偏振发光超分子有机凝胶。设计并合成了亲脂性鸟苷衍生物 (aldG)，用于形成明确的 G ₈ -八聚体。二胺连接体用于通过亚胺形成来连接G ₈ -八聚体单元，以促进超分子凝胶网络的构建。 ¹ H NMR 实验表明，预组装的 aldG _8-八聚体保持完整，对于透明和坚硬的有机凝胶的形成至关重要。通过延长的缀合时间，a​​ldG 有机凝胶无需任何外部荧光染料的帮助即可表现出强烈的绿色荧光发射和圆偏振特性，这为构建用于生物和材料应用的分子探针提供了另一种方法。