Purpose. To highlight the advantages of optical coherence tomography angiography (OCTA) in delineating the morphological features of the retinal and choroidal vascular network during acute, relapsing, and quiescent stages of macular toxoplasma retinochoroiditis. Methods. This prospective study included patients presenting with both active and quiescent ocular toxoplasmoses. OCTA was obtained to diagnose and follow the subsequent vascular network changes at diagnosis and six months after acute presentation. Results. Twenty-three eyes of 23 patients were included. In active lesions, OCTA showed extensive, well-delineated areas of intense hyposignal and perifoveal capillary arcade disruption in the parafoveal superficial capillary plexus (pSCP) and less extensive hyposignal in the parafoveal deep capillary plexus (pDCP). Signals of decreased deep capillary density and disorganization were also seen in the choroid. In nonactive lesions, OCTA demonstrated a homogenous and equally attenuated grayish hyposignal of the pSCP and pDCP and a partial restoration of the nonperfused choroidal areas. Conclusion. OCTA is a useful technique for vascular network analysis in toxoplasma retinochoroiditis. It allows the visualization of the different network changes and behaviors during the different stages of the infection.

中文翻译：

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黄斑弓形虫视网膜脉络膜炎急性、复发和静止期视网膜和脉络膜血管网络的光学相干断层扫描血管造影分析

目的。突出光学相干断层扫描血管造影 (OCTA) 在描述黄斑弓形虫视网膜脉络膜炎急性期、复发期和静止期视网膜和脉络膜血管网络形态特征方面的优势。方法。这项前瞻性研究包括患有活动性和静止性眼弓形虫病的患者。获得 OCTA 以诊断和跟踪诊断时和急性发作后六个月的随后血管网络变化。结果. 纳入 23 名患者的 23 只眼。在活动性病变中，OCTA 显示在中央凹浅表毛细血管丛 (pSCP) 中广泛的、清晰的低信号和中央凹周围毛细血管拱廊中断区域以及在中央凹深部毛细血管丛 (pDCP) 中的较不广泛的低信号。在脉络膜中也观察到深部毛细血管密度降低和组织紊乱的信号。在非活动性病变中，OCTA 显示出 pSCP 和 pDCP 的均匀且同样减弱的灰色低信号，以及未灌注的脉络膜区域的部分恢复。结论。OCTA 是一种用于弓形虫视网膜脉络膜炎血管网络分析的有用技术。它允许在感染的不同阶段可视化不同的网络变化和行为。