Background. Psoriasis is a chronic, inflammatory, and multifactorial dermatosis that impairs quality of life (QoL). Health-related QoL has become an important element in medical decision-making along with the effectiveness and the harmlessness of the treatments. Objective. To assess the impact of psoriasis in the QoL of patients with psoriasis by using the DLQI scales. Methods. A cross-sectional study from January to June 2018 was conducted in the Department of Dermatology of the University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar, including patients more than 18 years old with mild to severe psoriasis. The severity of psoriasis was assessed using the “Psoriasis Area and Severity Index (PASI)”. QoL of patients with psoriasis was evaluated by using the DLQI scales. Results. 80 patients were included, their mean age was 36.5 years, and the male to female was 1.5 : 1. The mean DLQI score was 13.8. Symptoms, feelings, and psychic were the most altered dimensions. QoL was impaired in young patients, single, having medium level education. Even though patients with disease duration more than 5 years had higher DLQI score than other patients, the difference was not statistically significant (). Furthermore, the clinical presentation of psoriasis did not influence the patient’s QoL (). Patients with nail involvement had QoL impaired but the difference with another localization was not statistically significant (). The quality of life was influenced by body area involved. The higher the body surface area involved, the more QoL is impaired (). Furthermore, the higher the PASI, the more QoL is altered (). Conclusion. Psoriasis has a negative impact in the quality of life in Malagasy patients with psoriasis, especially in younger and single patients. Worse quality of life is correlated to severity of psoriasis.

中文翻译：

---

马达加斯加塔那那利佛皮肤科银屑病患者的生活质量

背景。牛皮癣是一种慢性炎症性多因素皮肤病，会损害生活质量 (QoL)。与健康相关的生活质量以及治疗的有效性和无害性已成为医疗决策的重要因素。客观的。使用 DLQI 量表评估银屑病对银屑病患者生活质量的影响。方法。2018 年 1 月至 6 月，马达加斯加塔那那利佛大学医院 Joseph Raseta Befelatanana 皮肤科进行了一项横断面研究，研究对象包括 18 岁以上患有轻度至重度银屑病的患者。使用“银屑病面积和严重程度指数（PASI）”评估银屑病的严重程度。使用DLQI量表评估银屑病患者的生活质量。结果。纳入患者80例，平均年龄36.5岁，男女比例为1.5:1。平均DLQI评分为13.8。症状、感觉和心灵是变化最大的维度。受过中等教育的年轻单身患者的生活质量受到损害。尽管病程超过5年的患者DLQI评分高于其他患者，但差异无统计学意义（）。此外，银屑病的临床表现并不影响患者的生活质量（）。指甲受累的患者生活质量受损，但与其他部位的差异没有统计学意义（）。生活质量受到所涉及的身体部位的影响。涉及的体表面积越大，生活质量受损越多（）。此外，PASI 越高，生活质量改变越大（）。 结论。银屑病对马达加斯加银屑病患者的生活质量产生负面影响，尤其是年轻和单身患者。生活质量较差与牛皮癣的严重程度相关。