当前位置: X-MOL 学术ACS Pharmacol. Transl. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Achilles’ Heel of SARS-CoV-2 Structure
ACS Pharmacology & Translational Science ( IF 4.9 ) Pub Date : 2020-09-15 , DOI: 10.1021/acsptsci.0c00128
Ariel Fernández 1
Affiliation  

Guided by evolutionarily signaled vulnerabilities in the structure of SARS-CoV-2, we identify epitopes in free monomers of the spike protein that steer the generation of induced or administered antibodies geared at promoting destabilization of the virus quaternary structure, thereby hampering infectivity.

中文翻译:

SARS-CoV-2结构的阿喀琉斯之踵

在 SARS-CoV-2 结构中进化信号脆弱性的指导下,我们确定了刺突蛋白的游离单体中的表位,这些表位引导诱导或施用的抗体的产生,以促进病毒四级结构的不稳定,从而阻碍传染性。
更新日期:2020-10-11
down
wechat
bug