当前位置: X-MOL 学术J. Hered. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
AgeStrucNb: Software for Simulating and Detecting Changes in the Effective Number of Breeders (Nb)
Journal of Heredity ( IF 3.0 ) Pub Date : 2020-09-12 , DOI: 10.1093/jhered/esaa028
Tiago Antao 1 , Ted Cosart 2 , Brian Trethewey 3 , Robin S Waples 4 , Mike W Ackerman 5 , Gordon Luikart 1, 2 , Brian K Hand 1, 2
Affiliation  

Estimation of the effective number of breeders per reproductive event (Nb) using single sample DNA-marker-based methods has rapidly grown in recent years. However, estimating Nb is difficult in age-structured populations because the performance of estimators is influenced by the Nb / Ne ratio, which varies among species with different life histories. We provide a computer program, AgeStrucNb, to simulate age-structured populations (including life history) and also estimate Nb. The AgeStrucNb program is composed of 4 major components to simulate, subsample, estimate, and then visualize Nb time series data. AgeStrucNb allows users to also quantify the precision and accuracy of any set of loci or sample size to estimate Nb for many species and populations. AgeStrucNb allows users to conduct power analysis to evaluate sensitivity to detect changes in Nb or the power to detect a correlation between trends in Nb and environmental variables (e.g., temperature, habitat quality, predator or pathogen abundance) that could be driving changes in Nb. The software provides Nb estimates for empirical data sets using the LDNe (linkage disequilibrium) method, includes publication-quality output graphs, and outputs genotype files in Genepop format for use in other programs. AgeStrucNb will help advance the application of genetic markers for monitoring Nb, which will help biologists to detect population declines and growth, which is crucial for research and conservation of natural and managed populations.

中文翻译:

AgeStrucNb:用于模拟和检测育种者有效数量(N b)变化的软件

近年来,使用基于单个样本DNA标记的方法估算每个生殖事件(N b)育种者的有效数量已迅速增长。然而,估计Ñ b因为估计器的性能由影响在年龄结构种群难以Ñ b / Ñ ë比,这与不同的生活史物种的不同而不同。我们提供计算机程序AgeStrucNb,以模拟年龄结构化的人口(包括生活史)并估算N b。该AgeStrucNb程序被形象化由4个主要组分,以模拟,子样品,估计,然后N b个时间序列数据。AgeStrucNb允许用户量化任何基因座或样本大小的精确度和准确性,以估计许多物种和种群的N bAgeStrucNb允许用户行为功率分析来评价灵敏度以检测变化Ñ b或电源以检测趋势之间的相关性Ñ b和环境变量(例如,温度,栖息地质量,捕食或病原体丰度),可以在被驱动的变化ñ b。该软件提供N b使用LDNe(链接不平衡)方法对经验数据集进行估计,包括出版物质量的输出图,并以Genepop格式输出基因型文件,以供其他程序使用。AgeStrucNb将有助于推动遗传标记的应用监测ñ b,这将有助于生物学家探测人口下降和增长,这是自然的和管理的种群的研究和保护是至关重要的。
更新日期:2020-09-30
down
wechat
bug