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Shark: fishing relevant reads in an RNA-Seq sample.
Bioinformatics ( IF 4.4 ) Pub Date : 2020-09-14 , DOI: 10.1093/bioinformatics/btaa779
Luca Denti 1 , Yuri Pirola 1 , Marco Previtali 1 , Tamara Ceccato 1 , Gianluca Della Vedova 1 , Raffaella Rizzi 1 , Paola Bonizzoni 1
Affiliation  

Recent advances in high throughput RNA-Seq technologies allow to produce massive datasets. When a study focuses only on a handful of genes, most reads are not relevant and degrade the performance of the tools used to analyze the data. Removing irrelevant reads from the input dataset leads to improved efficiency without compromising the results of the study.

中文翻译:

鲨鱼:在 RNA-Seq 样本中钓鱼相关读数。

高通量 RNA-Seq 技术的最新进展允许生成大量数据集。当一项研究仅关注少数基因时,大多数读数都是不相关的,并且会降低用于分析数据的工具的性能。从输入数据集中删除不相关的读数可以提高效率,而不会影响研究结果。
更新日期:2020-09-15
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