Polycyclic aromatic hydrocarbons (PAHs) represent a class of organic compounds. Fish oil has been identified as one of the most important contributors to the level of persistent organic pollutants in foods. In fact, fish oils could contain elevated levels of lipophilic pollutants, such as PAHs due to the low metabolization capability of fish. The determination of PAHs in fish oils is complicated due to the fat matrix, which adversely affects both the extraction efficiency and analytical data quality. Target compounds were successfully extracted from nutritional supplements using fabric phase sorptive extraction (FPSE). For elution of the PAHs, the prepared sol-gel phenyl/polydimethylsiloxane (PDMS) coated fabric phase sorptive extraction membranes were back-extracted with acetonitrile and then eluted sample was analyzed by high-performance liquid chromatography (HPLC) with fluorescence detection. The PAHs were eluted on a C18 125 × 4 mm, 5 μm column, the oven temperature was 30 °C, and gradient elution was achieved with acetonitrile and water. The compounds were measured at wavelengths of 270 and 390 nm for pyrene and chrysene and 290 and 430 nm for benzo(a)pyrene. The method was validated in terms of linearity (2.5 to 75 ng/mL for pyrene and chrysene; 2.5 to 100 ng/mL for benzo(a)pyrene), precision and trueness (both intra- and inter-day), and recovery (from 63.2% to 102.3%). The obtained results by applying an innovative FPSE sampling/sample clean-up procedure which has recently shown its advantages in several applications for analysis of biological, environmental, cosmetic, and food matrices are presented in this work for the first time.

多环芳烃（PAH）代表一类有机化合物。鱼油被认为是食品中持久性有机污染物水平最重要的因素之一。实际上，由于鱼的新陈代谢能力低，鱼油中脂类污染物的含量可能较高，例如PAHs。鱼油中PAHs的测定由于脂肪基质而变得很复杂，这会对提取效率和分析数据质量产生不利影响。使用织物相吸附萃取（FPSE）从营养补品中成功提取了目标化合物。为了洗脱多环芳烃，用乙腈反萃取制备的溶胶-凝胶苯基/聚二甲基硅氧烷（PDMS）涂层的织物相吸附萃取膜，然后用高效液相色谱（HPLC）和荧光检测法分析洗脱的样品。PAHs在C18 125×4 mm，5μm色谱柱上洗脱，柱箱温度为30°C，并用乙腈和水进行梯度洗脱。在pyr和的波长为270和390 nm处，在苯并（a）re的波长为290和430 nm下测量化合物。方法的线性（（和丙烯为2.5至75 ng / mL;苯并（a）2.5为2.5至100 ng / mL），精密度和真实性（日内和日间）以及回收率（从63.2％至102.3％）。