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Identification of the metabolites of piperine via hepatocyte incubation and liquid chromatography combined with diode array detector and high-resolution mass spectrometry.
Rapid Communications in Mass Spectrometry ( IF 1.8 ) Pub Date : 2020-09-14 , DOI: 10.1002/rcm.8947 Yanping Li 1 , Ming Li 1 , Zhandi Wang 1 , Min Wen 2 , Jie Tang 3
Rapid Communications in Mass Spectrometry ( IF 1.8 ) Pub Date : 2020-09-14 , DOI: 10.1002/rcm.8947 Yanping Li 1 , Ming Li 1 , Zhandi Wang 1 , Min Wen 2 , Jie Tang 3
Affiliation
Piperine, an alkaloid isolated from Piper nigrum L, has been demonstrated to have many pharmacological effects and several health benefits. The aim of this study was to study the metabolic profiles of piperine in mouse, rat, dog and human hepatocytes.
中文翻译:
通过肝细胞培养和液相色谱结合二极管阵列检测器和高分辨率质谱鉴定胡椒碱的代谢产物。
Piperine是从Piper nigrum L分离得到的一种生物碱,已被证明具有许多药理作用和一些健康益处。这项研究的目的是研究胡椒碱在小鼠,大鼠,狗和人肝细胞中的代谢特性。
更新日期:2020-09-15
中文翻译:
通过肝细胞培养和液相色谱结合二极管阵列检测器和高分辨率质谱鉴定胡椒碱的代谢产物。
Piperine是从Piper nigrum L分离得到的一种生物碱,已被证明具有许多药理作用和一些健康益处。这项研究的目的是研究胡椒碱在小鼠,大鼠,狗和人肝细胞中的代谢特性。