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Myasthenia Gravis and Pregnancy.
Muscle & Nerve ( IF 2.8 ) Pub Date : 2020-09-14 , DOI: 10.1002/mus.27064
Kavita M Grover 1, 2 , Naganand Sripathi 1, 3
Affiliation  

Myasthenia gravis (MG) is an autoimmune disorder with bimodal age of presentation, occurring in young women of reproductive age and at an older age in men. Occasionally, MG is diagnosed during pregnancy. Management of MG includes symptomatic treatment with cholinesterase inhibitors and immunosuppressive therapy for controlling the disease activity. Treatment of MG in women of reproductive age, who may be contemplating pregnancy, requires discussion regarding the choice of medication as well as the understanding of risks/adverse effects involved with various treatments. During the peripartum period, it is essential to ensure careful monitoring of the disease state along with the well‐being of the mother and fetus and to coordinate neonatal monitoring overseen by a multidisciplinary team comprising a high‐risk maternal fetal medicine specialist, a neurologist familiar with these complex issues, and a neonatologist.

中文翻译:

重症肌无力和怀孕。

重症肌无力(MG)是一种具有双峰表现的自身免疫性疾病,多发于育龄的年轻女性,男性年龄较大。偶尔,MG在怀孕期间被诊断出。MG的管理包括用胆碱酯酶抑制剂对症治疗和控制疾病活动的免疫抑制疗法。对于可能正在考虑怀孕的育龄妇女的MG的治疗,需要就药物的选择以及对各种疗法涉及的风险/不良反应的理解进行讨论。在围产期,必须确保对疾病状态以及母亲和胎儿的健康状况进行仔细的监测,并协调由高风险孕妇医学专家组成的多学科团队对新生儿的监测,
更新日期:2020-11-19
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