当前位置: X-MOL 学术Reprod. Biomed. Online › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Fertility preservation during the COVID-19 pandemic: mitigating the viral contamination risk to reproductive cells in cryostorage
Reproductive BioMedicine Online ( IF 3.7 ) Pub Date : 2020-09-15 , DOI: 10.1016/j.rbmo.2020.09.013
Satish K Adiga 1 , Prathima Tholeti 1 , Shubhashree Uppangala 1 , Guruprasad Kalthur 1 , Roberto Gualtieri 2 , Riccardo Talevi 2
Affiliation  

Reopening fertility care services across the world in the midst of a pandemic brings with it numerous concerns that need immediate addressing, such as the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the male and female reproductive cells and the plausible risk of cross-contamination and transmission. Due to the novelty of the disease the literature contains few reports confirming an association of SARS-CoV-2 with reproductive tissues, gametes and embryos. Cryobanking, an essential service in fertility preservation, carries the risk of cross-contamination through cryogenic medium and thus calls for risk-mitigation strategies. This review aims to address the available literature on the presence of SARS-CoV-2 on tissues, gametes and embryos, with special reference to the possible sources of cross-contamination through liquid nitrogen. Strategies for risk mitigation have been extrapolated from reports dealing with other viruses to the current global crisis, for safety in fertility treatment services in general, and specifically for oncofertility.



中文翻译:


COVID-19 大流行期间的生育力保存:降低冷冻保存中生殖细胞的病毒污染风险



在大流行期间重新开放世界各地的生育护理服务带来了许多需要立即解决的问题,例如严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 对男性和女性生殖细胞的影响以及交叉污染和传播的合理风险。由于该疾病的新颖性,文献中很少有报告证实 SARS-CoV-2 与生殖组织、配子和胚胎的关联。冷冻银行是生育力保存的一项重要服务,存在低温介质交叉污染的风险,因此需要采取风险缓解策略。本综述旨在探讨有关组织、配子和胚胎上存在 SARS-CoV-2 的现有文献,特别提及液氮交叉污染的可能来源。风险缓解策略是从其他病毒的报告中推断出来的,以应对当前的全球危机,以确保生育治疗服务的安全,特别是肿瘤生育的安全。

更新日期:2020-09-15
down
wechat
bug