Multimorbidity (MM) is a widespread problem and it poses unsolved issues like the healthcare professionals’ training. A training curriculum has been proposed, but it has not been sufficiently explored in a clinical context. The eMULTIPAP course is part of the MULTIPAP complex intervention, applied through a pragmatic controlled, cluster randomized clinical trial to general practitioners (GP) and his/her patients with MM with 12 months follow-up. The eMULTIPAP course is based on problem-based learning, constructivism and Ariadne principles. It has been assessed according to the Kirkpatrick model and has shown knowledge improvement and high applicability of learning with more motivation to consider MM in the clinical practice. It has also improved the Medication Appropriateness Index at 6-months and at 12- months. We conclude that the eMULTIPAP course generates significant changes in GP’s learning, enhancing clinical practice in multimorbidity scenarios.

多发病 (MM) 是一个普遍存在的问题，它带来了未解决的问题，例如医疗保健专业人员的培训。已经提出了培训课程，但尚未在临床环境中进行充分探索。eMULTIPAP 课程是 MULTIPAP 综合干预的一部分，通过务实的对照、集群随机临床试验应用于全科医生 (GP) 及其 MM 患者，并进行 12 个月的随访。eMULTIPAP 课程基于基于问题的学习、建构主义和 Ariadne 原则。它已根据柯克帕特里克模型进行评估，并显示出知识改进和学习的高度适用性，更有动力在临床实践中考虑 MM。它还提高了 6 个月和 12 个月的药物适当性指数。