−A cost-effective flexible graphene working electrode (FGWE) was fabricated using overhead projector transparent film (OPTF) and a screen-printing technique. The surface morphology and electrochemical behavior of the electrode were characterized by scanning electron microscopy and cyclic voltammetry. The electrode presented a very thin layer of conductive ink (16.0 ± 0.7 µm) on a large effective surface area (0.301 ± 0.001 cm⁻²). The anodic peak current density (j_pa) of acetaminophen (ACT) in FGWE was 5.2, 3.7, 3.5 and 6.0 times greater than the j_pa of glassy carbon electrode (GCE), flexible carbon working electrode (FCWE), SPE1, and SPE2, respectively. The electrochemical performance of FGWE toward ACT was evaluated by differential pulse voltammetry. Under optimized condition, ACT was quantified in a range of 4-100 µM, with good sensitivity, good accuracy (recovery = 82.3 ± 0.4 to 106 ± 3%), and excellent precision. FGWE was applied to determine ACT in commercial pharmaceutical formulations. The results of the study are in good agreement with those obtained by the standard spectrophotometric method. These results indicate that disposable FGWE is particularly useful for the detection of ACT, and its performance may serve as a platform for cost-effective flexible electrochemical sensors.

-使用高架投影仪透明膜（OPTF）和丝网印刷技术制造了具有成本效益的柔性石墨烯工作电极（FGWE）。通过扫描电子显微镜和循环伏安法对电极的表面形貌和电化学行为进行了表征。电极在较大的有效表面积（0.301±0.001 cm ^-2）上呈现出非常薄的导电油墨层（16.0±0.7 µm ）。该阳极峰值电流密度（j _PA在FGWE对乙酰氨基酚）（ACT）为5.2，3.7，3.5和比第j大于6.0倍_PA分别为玻璃碳电极（GCE），柔性碳工作电极（FCWE），SPE1和SPE2。通过差动脉冲伏安法评估了FGWE对ACT的电化学性能。在优化的条件下，ACT的定量范围为4-100 µM，灵敏度高，准确度高（回收率= 82.3±0.4至106±3％），并且精密度高。FGWE用于测定商业药物制剂中的ACT。研究结果与通过标准分光光度法获得的结果相吻合。这些结果表明，一次性FGWE对ACT的检测特别有用，其性能可作为经济高效的柔性电化学传感器的平台。