Abstract

A Schiff base ligand derived from condensation of S-benzyldithiocarbazate (SBDTC) and salicylaldehyde, and its U(VI), Th(IV) and Zr(IV) complexes have been synthesized. The compounds are characterized by elemental analysis, molar conductance, magnetic moments, UV-Vis, FT-IR and ¹H NMR spectra. The Schiff base ligand coordinates via azomethine nitrogen, thiol sulfur and/or the phenolic OH group, and acts as bidentate in case of U(VI) and Zr(IV) ions and tridentate with Th(IV) ion. The U(VI) and Th(IV) complexes are 1 : 2 electrolytes whereas Zr(IV) complex is non-electrolytic. All the compounds have been tested for their antibacterial activity against four pathogenic bacteria, two Gram-negative Escherichia coli and Shigella dysenteriae and two Gram-positive Staphylococcus aureus and Bacillus subtilis using Kanamycin (K-30) as a standard. The U(VI) and Th(IV) complexes exhibit stronger antibacterial activity than the Zr(IV) complex against all tested organisms.

中文翻译：

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SBDTC衍生的席夫碱金属配合物：具有抗菌活性的合成，物理化学和光谱研究

摘要

合成了由S-苄基二硫代氨基甲酸酯（SBDTC）与水杨醛缩合形成的席夫碱配体及其U（VI），Th（IV）和Zr（IV）配合物。这些化合物的特征在于元素分析，摩尔电导，磁矩，UV-Vis，FT-IR和¹ H NMR光谱。席夫碱配体通过偶氮甲氮，硫醇硫和/或酚式OH基团进行配位，在U（VI）和Zr（IV）离子的情况下充当双齿，与Th（IV）离子的三齿起作用。U（VI）和Th（IV）配合物为1：2电解质，而Zr（IV）配合物为非电解质。已测试所有化合物对四种病原菌，两种革兰氏阴性大肠杆菌和痢疾志贺氏菌以及两种革兰氏阳性菌的抗菌活性。金黄色葡萄球菌和枯草芽孢杆菌以卡那霉素（K-30）为标准。与Zr（IV）配合物相比，U（VI）和Th（IV）配合物对所有测试生物显示出更强的抗菌活性。