Abstract

Novel bis-1,2,3-triazol-1H-4-yl-substituted aryl benzimidazole-2-thiol derivatives have been synthesized from 5-methoxy and 5-difluoromethoxy bis-propargyl substituted benzimidazole-2-thiols using the “click chemistry,” tested for their antimicrobial activity and subjected to molecular docking studies. Structures of the compounds have been elucidated from IR, NMR, and mass spectra.

中文翻译：

---

新型双-1,2,3-三唑-1 H -4-基取代的芳基苯并咪唑-2-硫醇衍生物的合成及抑菌活性

摘要

使用“点击”键，由5-甲氧基和5-二氟甲氧基双-炔丙基取代的苯并咪唑-2-硫醇合成了新的双1,2,3-三唑-1 H -4-基取代的芳基苯并咪唑-2-硫醇衍生物。化学”，测试其抗菌活性，并进行分子对接研究。化合物的结构已经从IR，NMR和质谱中阐明。