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Carbon fiber-reinforced PEEK versus titanium implants: an in vitro comparison of susceptibility artifacts in CT and MR imaging.
Neurosurgical Review ( IF 2.5 ) Pub Date : 2020-09-15 , DOI: 10.1007/s10143-020-01384-2
Theresa Krätzig 1 , Klaus C Mende 1 , Malte Mohme 1 , Helge Kniep 2 , Marc Dreimann 3 , Martin Stangenberg 3 , Manfred Westphal 1 , Tobias Gauer 4 , Sven O Eicker 1
Affiliation  

Artifacts in computed tomography (CT) and magnetic resonance imaging (MRI) due to titanium implants in spine surgery are known to cause difficulties in follow-up imaging, radiation planning, and precise dose delivery in patients with spinal tumors. Carbon fiber–reinforced polyetheretherketon (CFRP) implants aim to reduce these artifacts. Our aim was to analyze susceptibility artifacts of these implants using a standardized in vitro model. Titanium and CFRP screw-rod phantoms were embedded in 3% agarose gel. Phantoms were scanned with Siemens Somatom AS Open and 3.0-T Siemens Skyra scanners. Regions of interest (ROIs) were plotted and analyzed for CT and MRI at clinically relevant localizations. CT voxel–based imaging analysis showed a significant difference of artifact intensity and central overlay between titanium and CFRP phantoms. For the virtual regions of the spinal canal, titanium implants (ti) presented − 30.7 HU vs. 33.4 HU mean for CFRP (p < 0.001), at the posterior margin of the vertebral body 68.9 HU (ti) vs. 59.8 HU (CFRP) (p < 0.001) and at the anterior part of the vertebral body 201.2 HU (ti) vs. 70.4 HU (CFRP) (p < 0.001), respectively. MRI data was only visually interpreted due to the low sample size and lack of an objective measuring system as Hounsfield units in CT. CT imaging of the phantom with typical implant configuration for thoracic stabilization could demonstrate a significant artifact reduction in CFRP implants compared with titanium implants for evaluation of index structures. Radiolucency with less artifacts provides a better interpretation of follow-up imaging, radiation planning, and more precise dose delivery.



中文翻译:

碳纤维增强 PEEK 与钛植入物:CT 和 MR 成像中磁敏感伪影的体外比较。

众所周知,脊柱手术中钛植入物造成的计算机断层扫描 (CT) 和磁共振成像 (MRI) 中的伪影会给脊柱肿瘤患者的后续成像、放射计划和精确剂量输送带来困难。碳纤维增强聚醚醚酮 (CFRP) 植入物旨在减少这些伪影。我们的目标是使用标准化的体外模型分析这些植入物的易感性伪影。钛和 CFRP 螺杆模型被嵌入 3% 琼脂糖凝胶中。使用 Siemens Somatom AS Open 和 3.0-T Siemens Skyra 扫描仪扫描体模。绘制感兴趣区域 (ROI) 并在临床相关定位处对 CT 和 MRI 进行分析。基于 CT 体素的成像分析显示钛和 CFRP 体模之间的伪影强度和中心重叠存在显着差异。p  < 0.001),在椎体后缘 68.9 HU (ti) vs. 59.8 HU (CFRP) ( p  < 0.001) 和在椎体前部 201.2 HU (ti) vs. 70.4 HU (CFRP) ) ( p  < 0.001),分别。由于样本量小且缺乏像 CT 中的 Hounsfield 单位那样的客观测量系统,因此 MRI 数据只能在视觉上进行解释。与用于评估指标结构的钛植入物相比,具有用于胸部稳定的典型植入物配置的体模的 CT 成像可以证明,与钛植入物相比,CFRP 植入物显着减少了伪影。具有较少伪影的射线可透性可以更好地解释后续成像、放射计划和更精确的剂量输送。

更新日期:2020-09-15
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