Abamectin (Am) is an excellent biopesticide for insect pests control but environmental sensitivity and a short duration in conventional formulations limit its application in agriculture. In order to promote the dispersity, stability, and biological activity of Am, well-monodisperse nanochitin (NCh) and Am-loaded nanoparticles (NCh-Am) were prepared and examined in this study. NCh was prepared by ultrasonication combining with low concentration acidic hydrolysis and NCh-Am nanoparticles were combined by conjugation in dispersion naturally. The effective particle size of NCh was 110.6 ± 18.6 nm with cationic nature, while those of NCh-Am conjugates ranged from 160 to 700 nm based on the mixing ratio. The binding efficiency of Am to NCh in the conjugates reached 53.7 ± 7.6% in DI water at pH 6.2. The thermal stability and water solubility of Am were greatly promoted by NCh. The photodegradation of Am in the conjugates decreased 48% when exposed to UV light for 56 h. The conjugate containing half of Am showed significant control efficiency in larva growth and enhanced mortality against 2 instar larvae of noctuid. The results suggested that NCh significantly promoted Am water dispersity, thermal stability, and photostability, and effectively reduced pesticides dosage in insect pest control. This finding indicates that NCh-Am can be used as a new bioactive delivery system in future pest management.

阿维菌素（Amamectin，Am）是一种出色的害虫防治生物杀虫剂，但对环境的敏感性以及常规制剂的持续时间短，限制了其在农业中的应用。为了促进Am的分散性，稳定性和生物活性，本研究制备并检查了单分散性良好的纳米壳多糖（NCh）和载有Am的纳米颗粒（NCh-Am）。通过超声结合低浓度酸性水解制备NCh，并通过在分散体中自然偶联而结合NCh-Am纳米颗粒。NCh的有效粒径为110.6±18.6 nm，具有阳离子性质，而NCh-Am共轭物的有效粒径基于混合比在160至700 nm之间。在pH 6.2的去离子水中，Am与NCh在结合物中的结合效率达到53.7±7.6％。NCh大大提高了Am的热稳定性和水溶性。当暴露于紫外线下56 h时，缀合物中Am的光降解降低了48％。含有一半Am的结合物显示出对幼虫生长的显着控制效率，并且对2个夜蛾幼虫的死亡率提高了。结果表明，NCh显着促进了Am的水分散性，热稳定性和光稳定性，并有效减少了害虫防治中的农药用量。该发现表明，NCh-Am可以用作未来有害生物管理中的新生物活性传递系统。含有一半Am的结合物显示出对幼虫生长的显着控制效率，并提高了对抗2种夜蛾幼虫的死亡率。结果表明，NCh显着促进了Am的水分散性，热稳定性和光稳定性，并有效减少了害虫防治中的农药用量。这一发现表明，NCh-Am可以用作未来有害生物管理中的一种新的生物活性传递系统。含有一半Am的结合物显示出对幼虫生长的显着控制效率，并增加了对抗2种夜蛾幼虫的死亡率。结果表明，NCh显着促进了Am的水分散性，热稳定性和光稳定性，并有效减少了害虫防治中的农药用量。该发现表明，NCh-Am可以用作未来有害生物管理中的新生物活性传递系统。