Modern wound dressings not only play a covering role but also facilitate the function of the wound, contributing to a faster healing process. In this paper, we present a polyelectrolyte system with nanosized elements that could stimulate the growth of eukaryotic cells while providing antimicrobial properties, which may be recommended as a potential dressing material. The proposed platform consisted of polyethyleneimine, hydroxyapatite, and silver nanoparticles and was characterized using various macroscopic techniques. The constructed membrane scaffold was evaluated with immobilized WEHI 164 cells as a model system for cells sustained at the interface of bone and skin. Moreover, the bacteriostatic function of the designed membrane material was evaluated using different bacterial strains.

中文翻译：

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具有羟基磷灰石和纳米银的聚电解质膜作为现代伤口敷料的材料。

现代伤口敷料不仅起到覆盖作用，而且还促进了伤口的功能，有助于加快愈合过程。在本文中，我们提出了一种具有纳米级元素的聚电解质体系，该体系可以刺激真核细胞的生长，同时提供抗菌性能，因此可以推荐作为潜在的敷料。拟议的平台由聚乙烯亚胺，羟基磷灰石和银纳米颗粒组成，并使用各种宏观技术进行了表征。用固定的WEHI 164细胞作为在骨和皮肤界面处维持的细胞的模型系统，对构建的膜支架进行评估。此外，使用不同的细菌菌株评估了设计的膜材料的抑菌功能。