Rhenium-catalyzed alkylarylation of alkenes with PhI(O2CR)2via decarboxylation to access indolinones and dihydroquinolinones,Organic Chemistry Frontiers

当前位置： X-MOL 学术 › Org. Chem. Front. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Rhenium-catalyzed alkylarylation of alkenes with PhI(O2CR)2via decarboxylation to access indolinones and dihydroquinolinones
Organic Chemistry Frontiers ( IF 4.6 ) Pub Date : 2020-09-14 , DOI: 10.1039/d0qo00953a
Lei Zhang _{1,

2,

3,

4,

5} , Yin Wang _{6,

7,

8,

9,

10} , Yunhui Yang _{6,

7,

8,

9,

10} , Ping Zhang _{1,

2,

3,

4,

5} , Congyang Wang _{6,

7,

8,

9,

10}

Affiliation

Rhenium-catalyzed alkylarylation of alkenes with hypervalent iodine(III) reagents (HIRs) via decarboxylation to access various 3,3-disubstituted indolinones and trans-3,4-dihydroquinolinones is described. These transformations feature wide substrate scopes, good functional-group tolerance, and divergent regioselectivity. Mechanistic studies revealed a cascade sequence of decarboxylation/intermolecular radical alkylation/intramolecular radical arylation/oxidative re-aromatization.

中文翻译：

Ph通过羰基催化的PhI（O2CR）2烯烃与烯烃的烷基芳基化反应，以得到吲哚啉酮和二氢喹啉酮

描述了通过高羧基碘（III）试剂（HIR）进行的催化烯烃的烷基芳基化反应，从而获得各种3,3-二取代的吲哚啉酮和反式-3,4-二氢喹啉酮。这些转变具有广泛的底物范围，良好的官能团耐受性和不同的区域选择性。机理研究揭示了脱羧/分子间自由基烷基化/分子内自由基芳基化/氧化再芳构化的级联序列。

更新日期：2020-10-13

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11