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Ferroptosis in plants: triggers, proposed mechanisms, and the role of iron in modulating cell death
Journal of Experimental Botany ( IF 5.6 ) Pub Date : 2020-09-11 , DOI: 10.1093/jxb/eraa425
Ayelén Mariana Distéfano 1 , Gabriel Alejandro López 1 , Nicolás Setzes 1 , Fernanda Marchetti 1 , Maximiliano Cainzos 1 , Milagros Cascallares 1 , Eduardo Zabaleta 1 , Gabriela Carolina Pagnussat 1
Affiliation  

Abstract
Regulated cell death plays key roles during essential processes throughout the plant life cycle. It takes part in specific developmental programs and maintains homeostasis of the organism in response to unfavorable environments. Ferroptosis is a recently discovered iron-dependent cell death pathway characterized by the accumulation of lipid reactive oxygen species. In plants, ferroptosis shares all the main hallmarks described in other systems. Those specific features include biochemical and morphological signatures that seem to be conserved among species. However, plant cells have specific metabolic pathways and a high degree of metabolic compartmentalization. Together with their particular morphology, these features add more complexity to the plant ferroptosis pathway. In this review, we summarize the most recent advances in elucidating the roles of ferroptosis in plants, focusing on specific triggers, the main players, and underlying pathways.


中文翻译:

植物中的肥大病:触发因素,拟议的机制以及铁在调节细胞死亡中的作用

抽象的
在整个植物生命周期的关键过程中,调控细胞死亡起着关键作用。它参与特定的发展计划,并在不利的环境下保持有机体的体内平衡。Ferroptosis是最近发现的铁依赖性细胞死亡途径,其特征是脂质反应性氧的积累。在植物中,铁锈病具有其他系统中描述的所有主要特征。这些特定的特征包括似乎在物种之间是保守的生化和形态特征。但是,植物细胞具有特定的代谢途径和高度的代谢区室化。这些特征以及它们的特定形态,为植物受精除草剂的途径增加了更多的复杂性。在这篇评论中,
更新日期:2020-09-11
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