Abstract A total of 120 growing rabbits (7-weeks old) reared under high ambient temperature were divided into four equal groups, 30 rabbits each. The first group was received a basal diet without Phycocyanin (PC) (0 g/kg diet) and served as a control (PC0). The other three groups were received diets containing PC (50 (PC50), 100 (PC100), 150 (PC150) mg/kg diet, respectively). Live body weight (LBW) and feed conversion ratio (FCR) were enhanced significantly by 11.83% (p = .028) and 18.23% (p = .002) in PC50 group, and; respectively, compared with the PC0 group. Red blood cells, platelet, and haemoglobin values were significantly increased, while white blood cells were reduced (p = .033) in rabbits received diets containing PC (50, 100 and 150 mg/kg) compared to the PC0 group. Plasma urea, total bilirubin, and the gamma gamma-glutamyl transferase in the group PC100 were significantly higher than those in the PC group. Compared with the PC150 and control groups, treatment with 50 or 100 mg/kg decreased plasma interleukin-4 (p < .0001) and interferon γ (p < .0001) levels, but increased the levels of nitric oxide (p < .0001). Activities of antioxidants indices were improved (p < .0001) in the group treated with PC (50 and 100 mg/kg). However, lipid peroxidation (malondialdehyde) was decreased (p = .001) in PC50 compared with the other groups. The caecal bacterial populations were lowered in the groups treated with (50, 100 and 150 mg/kg) compared with those in the PC0 group. Conclusively, dietary inclusion of PC (100 mg/kg) could be effectively used to enhance the performance, antioxidants indices, decrease inflammatory responses and intestinal pathogens and hence enhance the health status of growing rabbits during the summer season. HIGHLIGHTS Phycocyanin (PC) is one of the most bioactive compounds of spirulina platensis. PC improved rabbit’s growth, immune, and antioxidants under heat stress.

中文翻译：

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日粮添加藻蓝蛋白对高环境温度下家兔生长的有益影响

摘要 将120只在高温环境下饲养的生长兔（7周龄）分成四等份，每组30只。第一组接受不含藻蓝蛋白 (PC) 的基础饮食（0 g/kg 饮食）并作为对照（PC0）。其他三组接受含有 PC 的饮食（分别为 50 (PC50)、100 (PC100)、150 (PC150) mg/kg 饮食）。PC50 组的活体重 (LBW) 和饲料转化率 (FCR) 显着提高了 11.83% (p = .028) 和 18.23% (p = .002)，并且；分别与 PC0 组进行比较。与 PC0 组相比，接受含有 PC（50、100 和 150 毫克/千克）的饮食的兔子的红细胞、血小板和血红蛋白值显着增加，而白细胞减少（p = .033）。血浆尿素、总胆红素、PC100组γ-谷氨酰转移酶显着高于PC组。与 PC150 和对照组相比，50 或 100 mg/kg 的处理降低了血浆白细胞介素 4 (p < .0001) 和干扰素 γ (p < .0001) 的水平，但增加了一氧化氮的水平 (p < .0001) ）。用 PC（50 和 100 mg/kg）治疗的组中抗氧化剂指数的活性得到改善（p < .0001）。然而，与其他组相比，PC50 中的脂质过氧化（丙二醛）降低（p = .001）。与 PC0 组相比，接受 (50、100 和 150 mg/kg) 治疗组的盲肠细菌数量有所降低。总之，膳食中含有 PC (100 mg/kg) 可以有效地用于提高性能、抗氧化剂指数、减少炎症反应和肠道病原体，从而提高夏季生长兔的健康状况。亮点 藻蓝蛋白 (PC) 是钝顶螺旋藻中最具生物活性的化合物之一。PC 在热应激下改善了兔子的生长、免疫和抗氧化剂。