ABSTRACT

Introduction

Electrospinning is a facile and viable method for the fabrication of nanofibers. Electrospun nanofiber has a great potential in providing local drug or therapeutic molecule delivery to the wound site. The versatile nature of this technique ensures a broad scope of material used in the fabrication of nanofibers.

Area covered

A brief introduction to diabetic foot ulcer (DFU) is covered with its pathogenesis, followed by the role of electrospun nanofibers in DFU. This review covers the evolution of the electrospinning technique over the past few years, various types of electrospun nanofibers reported for DFU or chronic diabetic wounds, the challenges associated with the preparation of nanofibers, and various methods to evaluate their efficacy and performance in diabetic wound healing.

Expert opinion

Electrospinning-based nanofibers provide a safe, effective, and multifunctional system for effective management of DFU.

中文翻译：

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基于静电纺丝纳米纤维的药物输送平台：糖尿病足溃疡管理的进步。

摘要

介绍

电纺丝是用于制造纳米纤维的简便且可行的方法。电纺纳米纤维在向伤口部位提供局部药物或治疗分子递送方面具有巨大潜力。该技术的通用性确保了用于制造纳米纤维的材料的广泛范围。

覆盖面积

糖尿病足溃疡（DFU）的发病机理以及对静电纺丝纳米纤维在DFU中的作用进行了简要介绍。这篇综述涵盖了过去几年电纺技术的发展，报道用于DFU或慢性糖尿病伤口的各种类型的电纺纳米纤维，与纳米纤维制备相关的挑战以及评估其在糖尿病伤口愈合中的功效和性能的各种方法。 。

专家意见

基于静电纺丝的纳米纤维为有效管理DFU提供了安全，有效和多功能的系统。