Respiratory failure (RF) is the main cause of hospital admission in HIV/AIDS patients. This study assessed comorbidities and laboratory parameters in HIV/AIDS inpatients with RF (N = 58) in relation to those without RF (N = 36). Tuberculosis showed a huge relative risk and platelet counts were slightly higher in HIV/AIDS inpatients with RF. A flow cytometry assay for reactive oxygen species (ROS) showed lower levels in platelets of these patients in relation to the healthy subjects. However, when stimulated with adrenaline, ROS levels increased in platelets and platelet-derived microparticles of HIV/AIDS inpatients, which may increase the risk of RF during HIV and tuberculosis (HIV-TB) coinfection.

中文翻译：

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艾滋病毒/艾滋病患者的血小板和血小板源微粒中的活性氧水平增加，并存在呼吸衰竭的风险。

呼吸衰竭（RF）是HIV / AIDS患者入院的主要原因。这项研究评估了有RF（N = 58）的有RF（N = 58）的HIV / AIDS住院患者的合并症和实验室参数。患有RF的HIV / AIDS病人，结核病显示出很高的相对风险，血小板计数略高。流式细胞仪检测活性氧（ROS）显示，与健康受试者相比，这些患者的血小板水平较低。但是，当用肾上腺素刺激时，HIV / AIDS患者的血小板和血小板衍生微粒中的ROS水平升高，这可能会增加HIV和结核病（HIV-TB）合并感染期间RF的风险。