Anti-CASPR2 antibody associated encephalitis with anosmia and demyelinating pseudotumor: A case report,Journal of Neuroimmunology

当前位置： X-MOL 学术 › J. Neuroimmunol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Anti-CASPR2 antibody associated encephalitis with anosmia and demyelinating pseudotumor: A case report
Journal of Neuroimmunology ( IF 2.9 ) Pub Date : 2020-11-01 , DOI: 10.1016/j.jneuroim.2020.577393
Xiang Xing ₁ , Jinmei Li ₂ , Siliang Chen ₁ , Linmao Zheng ₃ , Wentao Feng ₁ , Yanhui Liu ₁

Affiliation

A 20-year-old female presented with fine motor deficits and visual field defect was admitted to our hospital. CSF tests for autoimmune encephalitis antibodies and onconeuronal antibodies were unremarkable. MRI showed unilateral lesion involving left basal ganglia, external capsule, insula, hippocampus, and amygdala, which was considered to be demyelinating pseudotumor after surgical intervention. The patient's symptoms relieved so she didn't consent to immunotherapy. Two years and a half later our patient reported sudden anosmia. Reexamination by MRI demonstrated a new lesion. We then detected anti-CASPR2 antibodies in the patient's serum and gave her immunotherapy.

中文翻译：

抗CASPR2抗体相关性脑炎伴嗅觉丧失和脱髓鞘性假瘤一例

一名 20 岁女性因精细运动障碍和视野缺损入院。自身免疫性脑炎抗体和瘤神经元抗体的 CSF 检测无异常。MRI显示单侧病变累及左侧基底节、外囊、岛叶、海马、杏仁核，手术干预后考虑为脱髓鞘性假瘤。患者的症状有所缓解，因此她不同意进行免疫治疗。两年半后，我们的患者报告了突然的嗅觉丧失。MRI 复查显示有新的病变。然后我们在患者的血清中检测到了抗 CASPR2 抗体，并对其进行了免疫治疗。

更新日期：2020-11-01

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11