In this issue of Developmental Cell, Li et al. develop a novel lineage tracing system to record EMT activity during lung metastasis of mammary tumors. Using EMT-tracer mouse models, they reveal that N-cadherin is transiently expressed by most metastasis-initiating cells and demonstrate its functional importance during the metastatic cascade.

中文翻译：

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在转移过程中通过沿袭追踪记录EMT活性。

在本期《发育细胞》中，Li等人。开发一种新的谱系追踪系统，以记录乳腺肿瘤肺转移过程中的EMT活性。使用EMT-tracer小鼠模型，他们揭示了N-钙粘着蛋白在大多数转移起始细胞中瞬时表达，并在转移级联过程中证明了其功能重要性。