There has been a recent surge in the use of cryo and/or vacuum specimen preparation and transfer systems to broaden the scope of research enabled by the microscopy technique of atom probe tomography. This is driven by the fact that, as for many microscopes, the application of atom probes to air- and temperature-sensitive materials or wet biological specimens has previously been limited by transfer through air at room temperature. Here we provide an overview of areas of research that benefit from these new transfer and analysis protocols, as well as a review of current advances in transfer devices, environmental cells, and glove boxes for controlled specimen manipulation. This includes the study of catalysis and corrosion, biological samples, liquid-solid interfaces, natural aging, and the distribution of hydrogen in materials.

最近，使用冷冻和/或真空样品制备和转移系统以扩大由原子探针层析成像的显微技术实现的研究范围的热潮。这是因为，对于许多显微镜而言，原子探针在对空气和温度敏感的材料或潮湿的生物样本上的应用以前一直受到室温下空气转移的限制。在这里，我们概述了受益于这些新的转移和分析方案的研究领域，并概述了转移设备，环境池和用于控制标本处理的手套箱的最新进展。这包括对催化和腐蚀，生物样品，液固界面，自然老化以及材料中氢的分布的研究。