Biocompatibility of HEAs in the TiZrHfNbTa system in which all the constituents are non-toxic and allergy-free was scrutinized systematically, and novel biomechanical materials with a unique combination of low modulus (57 GPa, almost half that of conventional biomedical titanium alloys), good mechanical biocompatibility and low magnetic susceptibility (1.71 × 10⁻⁶ cm³ g⁻¹, similar to that of pure Zr) were successfully developed. Moreover, the underlying mechanisms responsible for phase formation and promising properties were explored. This work not only offers a series of novel bio-metallic materials with prominent properties for practical applications, but also shed light on understanding of phase formation and strengthening of HEAs in general.

系统检查了所有成分均为无毒且无过敏的TiZrHfNbTa系统中HEA的生物相容性，并结合了低模量（57 GPa，几乎是传统生物医学钛合金的一半）的独特组合的新型生物力学材料。机械生物相容性和低磁化率（1.71×10 ^-6  cm ³  g ^-1，与纯Zr相似）已得到成功开发。此外，探索了导致相形成和有希望的性质的潜在机制。这项工作不仅提供了一系列在实际应用中具有突出性能的新型生物金属材料，而且还使人们对一般的HEA的相形成和强化有了了解。