Tandem mass spectrometry (tandem MS) is a powerful technique that directly measures compounds based on their molecular weight. Liquid chromatography triple quadrupole mass spectrometry (LC-MS/MS), a type of tandem MS, has been increasingly adopted by clinical laboratories in recent years. While it is complicated and challenging, it has selectivity and accuracy advantages over more traditional laboratory techniques such as immunoassay. Able to measure a wide range of compounds, when correctly utilized and implemented, LC-MS/MS can benefit the clinical laboratory and improve patient care. This mini review is an introduction to clinical LC-MS/MS for the novice user.

串联质谱法（串联MS）是一项功能强大的技术，可根据其分子量直接测量化合物。液相色谱三重四极杆质谱（LC-MS / MS）是一种串联MS，近年来已被临床实验室越来越多地采用。尽管它很复杂且具有挑战性，但它具有比更传统的实验室技术（如免疫测定法）更高的选择性和准确性。如果正确使用和实施，LC-MS / MS能够测量各种化合物，可以使临床实验室受益并改善患者护理。这篇小型回顾是针对新手用户的临床LC-MS / MS简介。