A tandem method of synthesis of 3-hetaryl-4-nitrofuroxans was developed based on the one-pot sequence of thermolysis of 4-nitrofuroxannitrolic acid to the corresponding 4-nitro-3-furoxancarbonitrile oxide and [3+2] cycloaddition of the latter to acetylenes and olefins. It was established that the synthesized 3-(isoxazol-3-yl)- and 3-(isoxazolin-3-yl)-4-nitrofuroxans are formed with high regioand diastereoselectivity.

中文翻译：

---

由4-硝基呋喃恶烷硝酸合成3-Hetaryl-4-Nitrofuroxans的热解和[3 + 2]环加成串联反应。

基于4-硝基呋喃呋喃硝酸热解为相应的4-硝基-3-呋喃呋喃碳腈的一锅法和后者的[3 + 2]环加成反应，开发了一种串联合成3-杂芳基-4-硝基呋喃的方法乙炔和烯烃。已确定形成具有高区域选择性和非对映选择性的合成的3-（异恶唑-3-基）-和3-（异恶唑啉-3-基）-4-硝基呋喃。