ABSTRACT A novel hydroxyapatite/sodium alginate biocomposite doped with magnesium was developed to enhance the physical, mechanical and bioactivity properties in bone implant applications. Specifically, magnesium was doped in hydroxyapatite (HA) (Ca10(PO4)6(OH)2/sodium alginate (SA) (NaC6H7O) by using precipitation method. This research also explored the effects of magnesium doping on HA/SA samples. The prepared powder was uniaxially pressed and sintered at 1300°C. The characterisation of Mg-doped HA/SA at various concentration ranging from 0.5 wt-% to 1.5 wt-% were performed through Field Emission Scanning Electron Microscopy (FESEM) analysis. The maximum relative density and hardness of Mg-doped HA/SA were fixed at 92% and 4.11 GPa respectively and at 1.0 wt-% for samples of magnesium doping. Based on the microstructure analysis by FESEM it is evident that the elements were distributed evenly in Mg-doped hydroxyapatite/sodium alginate (HA/SA). These results proved that the Mg doping increased the physical, mechanical and bioactivity properties of HA/SA biocomposite.

中文翻译：

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镁掺杂对羟基磷灰石/海藻酸钠生物复合材料性能的影响

摘要开发了一种掺杂镁的新型羟基磷灰石/海藻酸钠生物复合材料，以增强骨植入物应用中的物理、机械和生物活性特性。具体而言，采用沉淀法将镁掺杂在羟基磷灰石 (HA) (Ca10(PO4)6(OH)2/海藻酸钠 (SA) (NaC6H7O) 中。本研究还探讨了镁掺杂对 HA/SA 样品的影响。制备的粉末在 1300°C 下单轴压制和烧结。通过场发射扫描电子显微镜 (FESEM) 分析对 0.5 wt-% 到 1.5 wt-% 不同浓度的 Mg 掺杂 HA/SA 进行表征。 Mg 掺杂的 HA/SA 的相对密度和硬度分别固定在 92% 和 4.11 GPa，而镁掺杂样品的相对密度和硬度固定在 1.0 wt-%。基于 FESEM 的微观结构分析，很明显元素均匀分布在 Mg 掺杂的羟基磷灰石/海藻酸钠 (HA/SA) 中。这些结果证明，Mg 掺杂提高了 HA/SA 生物复合材料的物理、机械和生物活性。