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The hot issue: TOR signalling network in plants.
Functional Plant Biology ( IF 3 ) Pub Date : 2020-09-10 , DOI: 10.1071/fp20071
Ying Zhao 1 , Xiu-Qin Wang 2
Affiliation  

The target of rapamycin (TOR) signalling network plays a pivotal role in regulating sugar metabolism and life-span in yeast, plants and mammals, in which TOR functions as a crucial protein. In plants, the TOR complex comprises TOR, RAPTOR (regulatory-associated protein of TOR) and LST8 (lethal with SEC13 protein 8). Factors like light, auxin, glucose, sucrose and amino acid can activate TOR protein as upstream signals to further phosphorylate downstream factors of TOR which promote cell proliferation and growth in plants. In this review, we analyse the TOR signalling network in plants and discuss the relationship between glucose and TOR, as well as the dynamic balance between TOR and sucrose-non-fermenting-related protein kinases (SnRKs). Given that 63 novel TOR-regulated proteins have been identified in previous studies, we also believe there are many unknown functions of TOR that need to be further investigated.



中文翻译:

热点问题:植物中的TOR信号网络。

雷帕霉素 (TOR) 信号网络的靶点在调节酵母、植物和哺乳动物的糖代谢和寿命方面发挥着关键作用,其中 TOR 是一种至关重要的蛋白质。在植物中,TOR 复合物包含 TOR、RAPTOR(TOR 的调节相关蛋白)和 LST8(与 SEC13 蛋白 8 一起致死)。光、生长素、葡萄糖、蔗糖和氨基酸等因子可以激活TOR蛋白作为上游信号,进一步磷酸化TOR下游因子,促进植物细胞增殖和生长。在这篇综述中,我们分析了植物中的 TOR 信号网络,并讨论了葡萄糖和 TOR 之间的关系,以及 TOR 和蔗糖非发酵相关蛋白激酶 (SnRKs) 之间的动态平衡。鉴于在先前的研究中已鉴定出 63 种新的 TOR 调节蛋白,

更新日期:2020-09-13
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