In vitro oral bioaccessibility assay (simple bioaccessibility extraction test) was used to assess bioaccessible PTEs (As, Cd, Co, Cu, Fe, Mn, Ni, Pb, Sn, and Zn) in 16 playground soils of Khagra, which is a medieval bell metal industrial town at Murshidabad district, West Bengal, India. The aim was also to establish levels of potentially toxic elements (PTEs) in soil, their origin, and human health risk, particularly on children. The average pseudo-total PTEs content in playground soil samples was in the decreasing order of Fe (18,988 mg kg⁻¹) > Zn (1229 mg kg⁻¹) > Cu (999 mg kg⁻¹) > Mn (343 mg kg⁻¹) > Pb (181 mg kg⁻¹) > Sn (132 mg kg⁻¹) > Co (8.63 mg kg⁻¹) > As (5.21 mg kg⁻¹) > Cd (0.88 mg kg⁻¹). The pollution indices indicate significant enrichment of Cd, Cu, Pb, Zn, and Sn in the playground. The bioaccessible percentage of PTEs in the 16 playground soils ranged from 0 to 80.25%, where the range of percentage of bioaccessibility was 13.24–62.50, 0–61.46, 16.82–28.79, 5.05–73.06, 0.96–6.14, 2.28–38, and 0–80 for As, Cd, Co, Cu, Fe, Ni, and Zn, respectively. The order of percentage of bioaccessibility was As > Mn > Zn > Sn > Cu > Co > Pb > Cd > Ni > Fe. PCA extracted two major factors indicating the anthropogenic (Cd, Cu, Ni, Pb, Zn, and Sn) and geogenic (Co, Fe, and Mn) source. Stepwise multiple regression analysis exhibited that the oral bioaccessibility of PTEs did not correlate with physicochemical parameters like pH, EC. In contrast, Sn had a significant correlation with that of organic matter. The health risk for pseudo-total as well as bioavailable fraction in playground soil depicted that children were more vulnerable to ingestion of soil contaminated with PTEs, particularly for Cu and Pb. A risk management plan with the bioaccessible data involving detailed site-specific exposure factors to indicate the importance of the study in terms of child health safety is required.

体外口腔生物可及性测定（简单生物可及性提取试验）用于评估卡格拉 16 个游乐场土壤中的生物可及性 PTE（As、Cd、Co、Cu、Fe、Mn、Ni、Pb、Sn 和 Zn）。印度西孟加拉邦穆尔希达巴德区的贝尔金属工业镇。其目的还在于确定土壤中潜在有毒元素 (PTE) 的水平、其来源以及人类健康风险，特别是对儿童的健康风险。游乐场土壤样品中PTEs的平均含量按从高到低的顺序排列为：Fe (18,988 mg kg ^-1 ) > Zn (1229 mg kg ^-1 ) > Cu (999 mg kg ^-1 ) > Mn (343 mg kg -1 ^{) 1} )>Pb(181mg kg ^-1 )>Sn(132mg kg ^-1 )>Co(8.63mg kg ^-1 )>As(5.21mg kg ^-1 )>Cd(0.88mg kg ^-1 )。污染指数表明游乐场内Cd、Cu、Pb、Zn、Sn显着富集。16个游乐场土壤中PTE的生物可利用百分比范围为0至80.25%，其中生物可访问百分比范围为13.24–62.50、0–61.46、16.82–28.79、5.05–73.06、0.96–6.14、2.28–38和As、Cd、Co、Cu、Fe、Ni 和 Zn 分别为 0–80。生物可及性百分比顺序为As>Mn>Zn>Sn>Cu>Co>Pb>Cd>Ni>Fe。PCA 提取了两个主要因素，表明人为来源（Cd、Cu、Ni、Pb、Zn 和 Sn）和地理来源（Co、Fe 和 Mn）。逐步多元回归分析表明，PTE 的口服生物可及性与 pH、EC 等理化参数不相关。相比之下，Sn与有机质的相关性显着。游乐场土壤中的假总和生物可利用部分的健康风险表明，儿童更容易摄入被 PTE（尤其是铜和铅）污染的土壤。需要制定风险管理计划，其中包含涉及详细的特定地点暴露因素的生物可访问数据，以表明研究在儿童健康安全方面的重要性。