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Epidemic Dynamics and Adaptive Vaccination Strategy: Renewal Equation Approach
Bulletin of Mathematical Biology ( IF 3.5 ) Pub Date : 2020-09-01 , DOI: 10.1007/s11538-020-00802-2
Aubain Nzokem 1 , Neal Madras 1
Affiliation  

We use analytical methods to investigate a continuous vaccination strategy's effects on the infectious disease dynamics in a closed population and a demographically open population. The methodology and key assumptions are based on Breda et al. (J Biol Dyn 6(Sup2):103-117, 2012). We show that the cumulative force of infection for the closed population and the endemic force of infection in the demographically open population can be reduced significantly by combining two factors: the vaccine effectiveness and the vaccination rate. The impact of these factors on the force of infection can transform an endemic steady state into a disease-free state.

中文翻译:

流行动态和适应性疫苗接种策略:更新方程方法

我们使用分析方法来研究连续疫苗接种策略对封闭人群和人口开放人群中传染病动态的影响。方法论和关键假设基于 Breda 等人。(J Biol Dyn 6(Sup2):103-117, 2012)。我们表明,通过结合两个因素:疫苗有效性和疫苗接种率,可以显着降低封闭人群的累积感染力和人口统计学开放人群的地方性感染力。这些因素对感染力的影响可以将地方性稳定状态转变为无病状态。
更新日期:2020-09-01
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