Abstract

Background:

The effect of the COVID-19 pandemic on people with Parkinson’s disease (PD) is poorly understood.

Objective:

To rapidly identify areas of need and improve care in people with PD during the COVID-19 pandemic, we deployed a survey to assess COVID-19 symptoms and the pandemic’s effect among those with and without COVID-19.

Methods:

People with and without PD participating in the online study Fox Insight (FI) were invited to complete a survey between April 23 and May 23, 2020. Among people reporting COVID-19 diagnoses, we compared symptoms and outcomes in people with and without PD. Among people not reporting COVID-19, we assessed access to healthcare and services and PD symptoms.

Results:

7,209/9,762 active FI users responded (approximately 74% response rate), 5,429 people with PD and 1,452 without PD. COVID-19 diagnoses were reported by 51 people with and 26 without PD. Complications were more frequent in people with longer PD duration. People with PD and COVID-19 experienced new or worsening motor (63%) and nonmotor (75%) symptoms. People with PD not diagnosed with COVID-19 reported disrupted medical care (64%), exercise (21%), and social activities (57%), and worsened motor (43%) and non-motor (52%) symptoms. Disruptions were more common for those living alone, with lower income and non-white race.

Conclusions:

The COVID-19 pandemic is associated with wide-ranging effects on people with PD, and certain groups may be at particular risk. FI provides a rapid, patient-centered means to assess these effects and identify needs that can be used to improve the health of people with PD.

中文翻译：

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COVID-19 大流行对帕金森病患者的影响。

摘要

背景：

人们对 COVID-19 大流行对帕金森病 (PD) 患者的影响知之甚少。

客观的：

为了在 COVID-19 大流行期间快速确定需要的领域并改善 PD 患者的护理，我们开展了一项调查，以评估 COVID-19 症状以及大流行对患有和未患有 COVID-19 的人的影响。

方法：

参加 Fox Insight (FI) 在线研究的患有和未患有 PD 的人受邀在 2020 年 4 月 23 日至 5 月 23 日期间完成一项调查。在报告 COVID-19 诊断的人群中，我们比较了患有和未患有 PD 的人的症状和结果。在未报告 COVID-19 的人群中，我们评估了获得医疗保健和服务的情况以及 PD 症状。

结果：

7,209/9,762 名活跃 FI 用户进行了回复（回复率约为 74%），其中 5,429 人患有 PD，1,452 人未患有 PD。51 名患有 PD 的人和 26 名未患有 PD 的人报告了 COVID-19 诊断。PD病程较长的人出现并发症的几率更高。PD 和 COVID-19 患者经历了新的或恶化的运动 (63%) 和非运动 (75%) 症状。未诊断出患有 COVID-19 的 PD 患者报告医疗护理 (64%)、运动 (21%) 和社交活动 (57%) 受到干扰，运动 (43%) 和非运动 (52%) 症状恶化。对于独居、收入较低和非白人种族的人来说，干扰更为常见。

结论：

COVID-19 大流行对帕金森病患者产生广泛影响，某些群体可能面临特别的风险。FI 提供了一种快速、以患者为中心的方法来评估这些影响并确定可用于改善 PD 患者健康的需求。