The Use of Autologous Matrix-Induced Chondrogenesis as a Surgical Treatment for Patients with the First Metatarsophalangeal Joint Osteoarthritis: Immediate and Medium-Term Results.,CARTILAGE

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The Use of Autologous Matrix-Induced Chondrogenesis as a Surgical Treatment for Patients with the First Metatarsophalangeal Joint Osteoarthritis: Immediate and Medium-Term Results.
CARTILAGE ( IF 2.7 ) Pub Date : 2020-09-11 , DOI: 10.1177/1947603520958127
Maxim Rinatovich Nurmukhametov ₁ , Maxim Anatolievich Makarov ₁ , Sergey Anatolievich Makarov ₁ , Evgeny Iosifovich Bialik ₁ , Valery Evgenievich Biaik ₁ , Vadim Andreevich Nesterenko ₁

Affiliation

Aim

To demonstrate the immediate and medium-term results of the surgical treatment of patients with first metatarsophalangeal (MTP) joint osteoarthritis (OA) using the autologous matrix-induced chondrogenesis (AMIC) technique and to evaluate the effectiveness.

Materials and Methods

Preoperatively the range of motion (ROM) in the first MTP joint was determined, and the following questionnaires were used: Visual Analogue Scale (VAS) of pain, American Orthopedic Foot & Ankle Society (AOFAS) score, and Functional Foot Index (FFI). All of the patients experienced a significant restriction of the ROM in the first MTP joint. The VAS of pain median was 70, AOFAS 52, and FFI 5.8.

Results

AMIC was performed in 19 patients with first MTP joint OA. All the patients experienced a significant restriction of ROM in the first MTP joint. The VAS of pain median was 70, AOFAS 52, and FFI 5.8. By the third month, VAS of pain decreased to 25, FFI to 2.2; AOFAS median increased to 77, ROM to 60°. Six months after the surgery VAS of pain decreased to 10, FFI to 1.1; AOFAS median increased to 90, ROM to 65°. After a year of observation, VAS of pain decreased to 5, FFI to 1,0; AOFAS median increased to 92.5, ROM to 71.5°.

Conclusion

The results showed that a first MTP joint AMIC procedure can be a fairly effective method of surgical treatment that can relieve pain and significantly improve the quality of life of patients with first MTP joint OA.

中文翻译：

使用自体基质诱导的软骨形成作为第一跖趾关节骨关节炎患者的手术治疗：即时和中期结果。

目标

证明使用自体基质诱导软骨形成 (AMIC) 技术对第一跖趾 (MTP) 关节骨关节炎 (OA) 患者进行手术治疗的近期和中期结果并评估其有效性。

材料和方法

术前确定第一跖趾关节的活动范围（ROM），并使用以下问卷：疼痛视觉模拟量表（VAS）、美国骨科足踝协会（AOFAS）评分和足部功能指数（FFI） . 所有患者都经历了第一个 MTP 关节 ROM 的显着限制。疼痛中位数的 VAS 为 70，AOFAS 为 52，FFI 为 5.8。

结果

对 19 名首次 MTP 关节 OA 患者进行 AMIC。所有患者均在第一跖趾关节出现明显的 ROM 受限。疼痛中位数的 VAS 为 70，AOFAS 为 52，FFI 为 5.8。到第三个月，疼痛的 VAS 降至 25，FFI 降至 2.2；AOFAS 中位数增加到 77，ROM 增加到 60°。术后 6 个月，疼痛 VAS 降至 10，FFI 降至 1.1；AOFAS 中位数增加到 90，ROM 增加到 65°。经过一年的观察，疼痛的 VAS 降至 5，FFI 降至 1.0；AOFAS 中位数增加到 92.5，ROM 增加到 71.5°。