Objective. The aim of this systematic review was to evaluate the effectiveness of laser application in temporomandibular joint disorder. Methods. PubMed, SCOPUS, Science Direct, Web of Science, and Google Scholar electronic databases were searched systematically with restricting the languages to only English and year (January 2001 to March 2020), and studies were selected based on the inclusion criteria. Study quality and publication bias were assessed by using the Robvis, a software package of R statistical software. Results. This systematic review included 32 studies (1172 patients) based on the inclusion and exclusion criteria. Most of the studies reported significant reduction of pain by the use of the laser during TMD treatment. Two-thirds of the study (78.13%) found a better outcome comparing with conventional one. According to Robvis, 84.4% of the studies were high methodological studies with low risk of bias. Conclusion. TMD patients suffer with continuous pain for long time even after conventional treatment. Laser therapy shows a promising outcome of pain reduction for TMD patients. Therefore, laser therapy can be recommended for the TMD patients’ better outcome. This trial is registered with PROSPERO (CRD42020177562).

中文翻译：

---

激光治疗颞下颌关节疾病的有效性：系统评价1172例患者

目标。该系统评价的目的是评估激光治疗颞下颌关节疾病的有效性。方法。系统地搜索PubMed，SCOPUS，Science Direct，Web of Science和Google Scholar电子数据库，并将语言限制为仅英语和年份（2001年1月至2020年3月），并根据纳入标准选择研究。研究质量和出版物偏倚通过使用Robvis（R统计软件的软件包）进行评估。结果。这项系统评价包括32项研究（1172例患者），基于纳入和排除标准。大多数研究报告称，在TMD治疗期间使用激光可显着减轻疼痛。三分之二的研究（78.13％）发现结果优于传统研究。根据Robvis的说法，其中有84.4％的研究是高方法学研究，偏倚风险低。结论。即使在常规治疗之后，TMD患者也遭受长时间持续疼痛。激光治疗对TMD患者显示出减轻疼痛的有希望的结果。因此，可以推荐激光治疗以使TMD患者获得更好的结果。该试用版已在PROSPERO（CRD42020177562）中注册。