One response to mitigate the impact of climate change on agricultural systems is to develop new varieties that are tolerant to the new range of biotic and abiotic challenges this change causes. This requires access to novel variants of genes for complex adaptive traits. Crop wild relatives are a potentially valuable source of these genes however these materials are often difficult to work with and identifying valuable alleles is difficult without substantial investment in pre-breeding. In this study we describe the development of a nested association mapping population for sorghum using two cultivated grain sorghum reference parents and 9 wild and exotic sorghum accessions as donors. The donor parents come from the verticilliflorum, drummondii and margaritiferum taxa and were sampled from a range of environments across Africa. In total the resource of consists of 13 populations and a total of 1,224 lines. The population has been genotyped with DArT markers which produced 42,372 unique SNP markers covering the genome. We determine the utility of the resource for high resolution mapping of complex traits by demonstrating that the exotics contain unique alleles for some example adaptive trait loci and by using the population for GWAS. The resource should provide useful material for plant breeders attempting to deal with the challenges generated by climate change. This article is protected by copyright. All rights reserved

中文翻译：

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探索和利用高粱作物野生近缘种遗传变异的全球资源

减轻气候变化对农业系统影响的一种应对措施是开发新品种，以应对这种变化引起的一系列新的生物和非生物挑战。这需要获得具有复杂适应性特征的基因的新变体。作物野生近缘种是这些基因的潜在有价值的来源，但是这些材料通常很难使用，并且如果没有对预育种进行大量投资，则很难识别有价值的等位基因。在这项研究中，我们描述了使用两个栽培谷物高粱参考亲本和 9 个野生和外来高粱种质作为供体的高粱嵌套关联映射种群的开发。供体亲本来自 verticilliflorum、drummondii 和 margaritiferum 类群，并从非洲的一系列环境中取样。总共有13个种群和1,224行的资源。该群体已使用 DArT 标记进行基因分型，产生了 42,372 个覆盖基因组的独特 SNP 标记。我们通过证明外来物种包含某些示例适应性性状基因座的独特等位基因并通过使用 GWAS 的种群来确定资源对复杂性状的高分辨率映射的效用。该资源应为试图应对气候变化带来的挑战的植物育种者提供有用的材料。本文受版权保护。版权所有 我们通过证明外来物种包含某些示例适应性性状基因座的独特等位基因并通过使用 GWAS 的种群来确定资源对复杂性状的高分辨率映射的效用。该资源应为试图应对气候变化带来的挑战的植物育种者提供有用的材料。本文受版权保护。版权所有 我们通过证明外来物种包含某些示例适应性性状基因座的独特等位基因并通过使用 GWAS 的种群来确定资源对复杂性状的高分辨率映射的效用。该资源应为试图应对气候变化带来的挑战的植物育种者提供有用的材料。本文受版权保护。版权所有