An intimate interplay of the plasma membrane with curvature-sensing and curvature-inducing proteins would allow for defining specific sites or nanodomains of action at the plasma membrane, for example, for protrusion, invagination, and polarization. In addition, such connections are predestined to ensure spatial and temporal order and sequences. The combined forces of membrane shapers and the cortical actin cytoskeleton might hereby in particular be required to overcome the strong resistance against membrane rearrangements in case of high plasma membrane tension or cellular turgor. Interestingly, also the opposite might be necessary, the inhibition of both membrane shapers and cytoskeletal reinforcement structures to relieve membrane tension to protect cells from membrane damage and rupturing during mechanical stress. In this review article, we discuss recent conceptual advances enlightening the interplay of plasma membrane curvature and the cortical actin cytoskeleton during endocytosis, modulations of membrane tensions, and the shaping of entire cells.

质膜与曲率感应和曲率诱导蛋白的紧密相互作用将允许在质膜上定义特定的作用位点或纳米域，例如用于突出，内陷和极化。另外，这种连接注定要确保空间和时间顺序和顺序。因此，在高血浆膜张力或细胞膨胀的情况下，可能特别需要膜整形器和皮质肌动蛋白细胞骨架的组合力来克服对膜重排的强抵抗力。有趣的是，相反的可能是必要的，即对膜整形器和细胞骨架增强结构的抑制，以减轻膜张力，以保护细胞免受机械应力作用下的膜损伤和破裂。在这篇评论文章中，